Long-read sequencing for 29 immune cell subsets reveals disease-linked isoforms.
Inamo J, Suzuki A, Ueda MT, Yamaguchi K, Nishida H, Suzuki K, Kaneko Y, Takeuchi T, Hatano H, Ishigaki K, Ishihama Y, Yamamoto K, Kochi Y.
Inamo J, et al.
Nat Commun. 2024 May 28;15(1):4285. doi: 10.1038/s41467-024-48615-4.
Nat Commun. 2024.
PMID: 38806455
Free PMC article.
Here, we generate a full-length isoform annotation of human immune cells from an individual by long-read sequencing for 29 cell subsets. This contains a number of unannotated transcripts and isoforms such as a read-through transcript of TOMM40-APOE in the Alzheimer's disea …
Here, we generate a full-length isoform annotation of human immune cells from an individual by long-read sequencing for 29 cell subsets. Thi …