H-1006/PUK_/Parkinson's UK/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2011	1
2012	1
2013	3
2014	2
2015	1
2016	3
2017	2
2025	0

1

The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease.

Wood-Kaczmar A, Deas E, Wood NW, Abramov AY. Wood-Kaczmar A, et al. Adv Exp Med Biol. 2013;961:241-9. doi: 10.1007/978-1-4614-4756-6_20. Adv Exp Med Biol. 2013. PMID: 23224884 Review.

2

The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy.

Burchell VS, Nelson DE, Sanchez-Martinez A, Delgado-Camprubi M, Ivatt RM, Pogson JH, Randle SJ, Wray S, Lewis PA, Houlden H, Abramov AY, Hardy J, Wood NW, Whitworth AJ, Laman H, Plun-Favreau H. Burchell VS, et al. Nat Neurosci. 2013 Sep;16(9):1257-65. doi: 10.1038/nn.3489. Epub 2013 Aug 11. Nat Neurosci. 2013. PMID: 23933751 Free PMC article.

3

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease.

Deas E, Cremades N, Angelova PR, Ludtmann MH, Yao Z, Chen S, Horrocks MH, Banushi B, Little D, Devine MJ, Gissen P, Klenerman D, Dobson CM, Wood NW, Gandhi S, Abramov AY. Deas E, et al. Antioxid Redox Signal. 2016 Mar 1;24(7):376-91. doi: 10.1089/ars.2015.6343. Epub 2016 Feb 1. Antioxid Redox Signal. 2016. PMID: 26564470 Free PMC article.

4

Ca2+ is a key factor in α-synuclein-induced neurotoxicity.

Angelova PR, Ludtmann MH, Horrocks MH, Negoda A, Cremades N, Klenerman D, Dobson CM, Wood NW, Pavlov EV, Gandhi S, Abramov AY. Angelova PR, et al. J Cell Sci. 2016 May 1;129(9):1792-801. doi: 10.1242/jcs.180737. Epub 2016 Mar 17. J Cell Sci. 2016. PMID: 26989132 Free PMC article.

5

Dopamine protects neurons against glutamate-induced excitotoxicity.

Vaarmann A, Kovac S, Holmström KM, Gandhi S, Abramov AY. Vaarmann A, et al. Cell Death Dis. 2013 Jan 10;4(1):e455. doi: 10.1038/cddis.2012.194. Cell Death Dis. 2013. PMID: 23303129 Free PMC article.

6

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease.

Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM. Tufi R, et al. Nat Cell Biol. 2014 Feb;16(2):157-66. doi: 10.1038/ncb2901. Epub 2014 Jan 19. Nat Cell Biol. 2014. PMID: 24441527 Free PMC article.

7

Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading.

Iljina M, Garcia GA, Horrocks MH, Tosatto L, Choi ML, Ganzinger KA, Abramov AY, Gandhi S, Wood NW, Cremades N, Dobson CM, Knowles TP, Klenerman D. Iljina M, et al. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1206-15. doi: 10.1073/pnas.1524128113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884195 Free PMC article.

8

Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function.

Fitzgerald JC, Camprubi MD, Dunn L, Wu HC, Ip NY, Kruger R, Martins LM, Wood NW, Plun-Favreau H. Fitzgerald JC, et al. Cell Death Differ. 2012 Feb;19(2):257-66. doi: 10.1038/cdd.2011.90. Epub 2011 Jun 24. Cell Death Differ. 2012. PMID: 21701498 Free PMC article.

9

Early Onset Parkinson's Disease in a family of Moroccan origin caused by a p.A217D mutation in PINK1: a case report.

Norman BP, Lubbe SJ, Tan M, Warren N, Morris HR. Norman BP, et al. BMC Neurol. 2017 Aug 8;17(1):153. doi: 10.1186/s12883-017-0933-z. BMC Neurol. 2017. PMID: 28789629 Free PMC article.

10

Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations.

Lynch DS, Loh SHY, Harley J, Noyce AJ, Martins LM, Wood NW, Houlden H, Plun-Favreau H. Lynch DS, et al. Neurol Genet. 2017 Sep 22;3(5):e188. doi: 10.1212/NXG.0000000000000188. eCollection 2017 Oct. Neurol Genet. 2017. PMID: 28955727 Free PMC article. No abstract available.

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