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Macrophages and nociceptor neurons form a sentinel unit around fenestrated capillaries to defend the synovium from circulating immune challenge.
Hasegawa T, Lee CYC, Hotchen AJ, Fleming A, Singh R, Suzuki K, Yuzaki M, Watanabe M, Birch MA, McCaskie AW, Lénárt N, Tóth K, Dénes Á, Liu Z, Ginhoux F, Richoz N, Clatworthy MR. Hasegawa T, et al. Nat Immunol. 2024 Dec;25(12):2270-2283. doi: 10.1038/s41590-024-02011-8. Epub 2024 Nov 25. Nat Immunol. 2024. PMID: 39587345 Free PMC article.