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Page 1
Haematopoietic stem and progenitor cells from human pluripotent stem cells.
Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ. Sugimura R, et al. Nature. 2017 May 25;545(7655):432-438. doi: 10.1038/nature22370. Epub 2017 May 17. Nature. 2017. PMID: 28514439 Free PMC article.
Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.
Banerjee A, Herring CA, Chen B, Kim H, Simmons AJ, Southard-Smith AN, Allaman MM, White JR, Macedonia MC, Mckinley ET, Ramirez-Solano MA, Scoville EA, Liu Q, Wilson KT, Coffey RJ, Washington MK, Goettel JA, Lau KS. Banerjee A, et al. Gastroenterology. 2020 Dec;159(6):2101-2115.e5. doi: 10.1053/j.gastro.2020.08.029. Epub 2020 Aug 21. Gastroenterology. 2020. PMID: 32828819 Free PMC article.
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.
Ryzhakov G, West NR, Franchini F, Clare S, Ilott NE, Sansom SN, Bullers SJ, Pearson C, Costain A, Vaughan-Jackson A, Goettel JA, Ermann J, Horwitz BH, Buti L, Lu X, Mukhopadhyay S, Snapper SB, Powrie F. Ryzhakov G, et al. Nat Commun. 2018 Sep 18;9(1):3797. doi: 10.1038/s41467-018-06085-5. Nat Commun. 2018. PMID: 30228258 Free PMC article.
Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation.
Tsou AM, Goettel JA, Bao B, Biswas A, Kang YH, Redhu NS, Peng K, Putzel GG, Saltzman J, Kelly R, Gringauz J, Barends J, Hatazaki M, Frei SM, Emani R, Huang Y, Shen Z, Fox JG, Glickman JN, Horwitz BH, Snapper SB. Tsou AM, et al. Microbiome. 2021 Nov 3;9(1):215. doi: 10.1186/s40168-021-01161-3. Microbiome. 2021. PMID: 34732258 Free PMC article.
Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model.
Goettel JA, Kotlarz D, Emani R, Canavan JB, Konnikova L, Illig D, Frei SM, Field M, Kowalik M, Peng K, Gringauz J, Mitsialis V, Wall SM, Tsou A, Griffith AE, Huang Y, Friedman JR, Towne JE, Plevy SE, O'Hara Hall A, Snapper SB. Goettel JA, et al. Cell Mol Gastroenterol Hepatol. 2019;8(2):193-195. doi: 10.1016/j.jcmgh.2019.05.001. Epub 2019 May 9. Cell Mol Gastroenterol Hepatol. 2019. PMID: 31078723 Free PMC article. No abstract available.