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Page 1
Branched-chain amino acids in cardiovascular disease.
McGarrah RW, White PJ. McGarrah RW, et al. Nat Rev Cardiol. 2023 Feb;20(2):77-89. doi: 10.1038/s41569-022-00760-3. Epub 2022 Sep 5. Nat Rev Cardiol. 2023. PMID: 36064969 Free PMC article. Review.
Cardiovascular Metabolomics.
McGarrah RW, Crown SB, Zhang GF, Shah SH, Newgard CB. McGarrah RW, et al. Circ Res. 2018 Apr 27;122(9):1238-1258. doi: 10.1161/CIRCRESAHA.117.311002. Circ Res. 2018. PMID: 29700070 Free PMC article. Review.
The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.
White PJ, McGarrah RW, Grimsrud PA, Tso SC, Yang WH, Haldeman JM, Grenier-Larouche T, An J, Lapworth AL, Astapova I, Hannou SA, George T, Arlotto M, Olson LB, Lai M, Zhang GF, Ilkayeva O, Herman MA, Wynn RM, Chuang DT, Newgard CB. White PJ, et al. Cell Metab. 2018 Jun 5;27(6):1281-1293.e7. doi: 10.1016/j.cmet.2018.04.015. Epub 2018 May 17. Cell Metab. 2018. PMID: 29779826 Free PMC article.
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart.
Walejko JM, Christopher BA, Crown SB, Zhang GF, Pickar-Oliver A, Yoneshiro T, Foster MW, Page S, van Vliet S, Ilkayeva O, Muehlbauer MJ, Carson MW, Brozinick JT, Hammond CD, Gimeno RE, Moseley MA, Kajimura S, Gersbach CA, Newgard CB, White PJ, McGarrah RW. Walejko JM, et al. Nat Commun. 2021 Mar 15;12(1):1680. doi: 10.1038/s41467-021-21962-2. Nat Commun. 2021. PMID: 33723250 Free PMC article.