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A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.
Moll M, Peljto AL, Kim JS, Xu H, Debban CL, Chen X, Menon A, Putman RK, Ghosh AJ, Saferali A, Nishino M, Hatabu H, Hobbs BD, Hecker J, McDermott G, Sparks JA, Wain LV, Allen RJ, Tobin MD, Raby BA, Chun S, Silverman EK, Zamora AC, Ortega VE, Garcia CK, Barr RG, Bleecker ER, Meyers DA, Kaner RJ, Rich SS, Manichaikul A, Rotter JI, Dupuis J, O'Connor GT, Fingerlin TE, Hunninghake GM, Schwartz DA, Cho MH. Moll M, et al. Am J Respir Crit Care Med. 2023 Oct 1;208(7):791-801. doi: 10.1164/rccm.202212-2257OC. Am J Respir Crit Care Med. 2023. PMID: 37523715 Free PMC article.
Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease.
Moll M, Sordillo JE, Ghosh AJ, Hayden LP, McDermott G, McGeachie MJ, Dahlin A, Tiwari A, Manmadkar MG, Abston ED, Pavuluri C, Saferali A, Begum S, Ziniti JP, Gulsvik A, Bakke PS, Aschard H, Iribarren C, Hersh CP, Sparks JA, Hobbs BD, Lasky-Su JA, Silverman EK, Weiss ST, Wu AC, Cho MH. Moll M, et al. J Allergy Clin Immunol. 2023 Dec;152(6):1423-1432. doi: 10.1016/j.jaci.2023.08.002. Epub 2023 Aug 16. J Allergy Clin Immunol. 2023. PMID: 37595761 Free PMC article.
Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores.
Hrytsenko Y, Shea B, Elgart M, Kurniansyah N, Lyons G, Morrison AC, Carson AP, Haring B, Mitchell BD, Psaty BM, Jaeger BC, Gu CC, Kooperberg C, Levy D, Lloyd-Jones D, Choi E, Brody JA, Smith JA, Rotter JI, Moll M, Fornage M, Simon N, Castaldi P, Casanova R, Chung RH, Kaplan R, Loos RJF, Kardia SLR, Rich SS, Redline S, Kelly T, O'Connor T, Zhao W, Kim W, Guo X, Ida Chen YD; Trans-Omics in Precision Medicine Consortium; Sofer T. Hrytsenko Y, et al. Sci Rep. 2024 May 30;14(1):12436. doi: 10.1038/s41598-024-62945-9. Sci Rep. 2024. PMID: 38816422 Free PMC article.
Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores.
Hrytsenko Y, Shea B, Elgart M, Kurniansyah N, Lyons G, Morrison AC, Carson AP, Haring B, Mitchel BD, Psaty BM, Jaeger BC, Gu CC, Kooperberg C, Levy D, Lloyd-Jones D, Choi E, Brody JA, Smith JA, Rotter JI, Moll M, Fornage M, Simon N, Castaldi P, Casanova R, Chung RH, Kaplan R, Loos RJF, Kardia SLR, Rich SS, Redline S, Kelly T, O'Connor T, Zhao W, Kim W, Guo X, Der Ida Chen Y; Trans-Omics in Precision Medicine Consortium; Sofer T. Hrytsenko Y, et al. medRxiv [Preprint]. 2023 Dec 14:2023.12.13.23299909. doi: 10.1101/2023.12.13.23299909. medRxiv. 2023. Update in: Sci Rep. 2024 May 30;14(1):12436. doi: 10.1038/s41598-024-62945-9 PMID: 38168328 Free PMC article. Updated. Preprint.
Development, Progression, and Mortality of Suspected Interstitial Lung Disease in COPDGene.
Rose JA, Tukpah AC, Cutting C, Wada N, Nishino M, Moll M, Kalra S, Choi B, Lynch DA, Raby BA, Rosas IO, San José Estépar R, Washko GR, Silverman EK, Cho MH, Hatabu H, Putman RK, Hunninghake GM. Rose JA, et al. Am J Respir Crit Care Med. 2024 Dec 15;210(12):1453-1460. doi: 10.1164/rccm.202402-0313OC. Am J Respir Crit Care Med. 2024. PMID: 39133466
Genomic and Serological Rheumatoid Arthritis Biomarkers, MUC5B Promoter Variant, and Interstitial Lung Abnormalities.
Kim JS, Flack KF, Malik V, Manichaikul A, Sakaue S, Luo Y, McGroder CF, Salvatore M, Anderson MR, Hoffman EA, Podolanczuk AJ, Yun JH, McDermott GC, Sparks JA, Putman R, Moll M, Rich SS, Rotter JI, Noth I, Raghu G, Giles JT, Winchester R, Raychaudhuri S, Hunninghake GM, Cho MH, Garcia CK, Barr RG, Bernstein EJ. Kim JS, et al. Ann Am Thorac Soc. 2024 Oct 15. doi: 10.1513/AnnalsATS.202403-238OC. Online ahead of print. Ann Am Thorac Soc. 2024. PMID: 39405163
A polygenic risk score and age of diagnosis of COPD.
Zhang J, Xu H, Qiao D, DeMeo DL, Silverman EK, O'Connor GT, Hobbs BD, Dupuis J, Cho MH, Moll M. Zhang J, et al. Eur Respir J. 2022 Sep 15;60(3):2101954. doi: 10.1183/13993003.01954-2021. Print 2022 Sep. Eur Respir J. 2022. PMID: 35115341 Free PMC article.
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