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ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA.
Zhang H, Head PE, Daddacha W, Park SH, Li X, Pan Y, Madden MZ, Duong DM, Xie M, Yu B, Warren MD, Liu EA, Dhere VR, Li C, Pradilla I, Torres MA, Wang Y, Dynan WS, Doetsch PW, Deng X, Seyfried NT, Gius D, Yu DS. Zhang H, et al. Cell Rep. 2016 Feb 16;14(6):1435-1447. doi: 10.1016/j.celrep.2016.01.018. Epub 2016 Feb 4. Cell Rep. 2016. PMID: 26854234 Free PMC article.
SIRT2 directs the replication stress response through CDK9 deacetylation.
Zhang H, Park SH, Pantazides BG, Karpiuk O, Warren MD, Hardy CW, Duong DM, Park SJ, Kim HS, Vassilopoulos A, Seyfried NT, Johnsen SA, Gius D, Yu DS. Zhang H, et al. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13546-51. doi: 10.1073/pnas.1301463110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898190 Free PMC article.