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Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition.
Nature. 2020 Jan;577(7790):421-425. doi: 10.1038/s41586-019-1884-x. Epub 2020 Jan 8.
Nature. 2020.
PMID: 31915379
Free PMC article.
Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism.
Lito P, Solomon M, Li LS, Hansen R, Rosen N.
Lito P, et al.
Science. 2016 Feb 5;351(6273):604-8. doi: 10.1126/science.aad6204. Epub 2016 Jan 14.
Science. 2016.
PMID: 26841430
Free PMC article.
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