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Page 1
Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes.
De Sarkar N, Patton RD, Doebley AL, Hanratty B, Adil M, Kreitzman AJ, Sarthy JF, Ko M, Brahma S, Meers MP, Janssens DH, Ang LS, Coleman IM, Bose A, Dumpit RF, Lucas JM, Nunez TA, Nguyen HM, McClure HM, Pritchard CC, Schweizer MT, Morrissey C, Choudhury AD, Baca SC, Berchuck JE, Freedman ML, Ahmad K, Haffner MC, Montgomery RB, Corey E, Henikoff S, Nelson PS, Ha G. De Sarkar N, et al. Cancer Discov. 2023 Mar 1;13(3):632-653. doi: 10.1158/2159-8290.CD-22-0692. Cancer Discov. 2023. PMID: 36399432 Free PMC article.
A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA.
Doebley AL, Ko M, Liao H, Cruikshank AE, Santos K, Kikawa C, Hiatt JB, Patton RD, De Sarkar N, Collier KA, Hoge ACH, Chen K, Zimmer A, Weber ZT, Adil M, Reichel JB, Polak P, Adalsteinsson VA, Nelson PS, MacPherson D, Parsons HA, Stover DG, Ha G. Doebley AL, et al. Nat Commun. 2022 Dec 3;13(1):7475. doi: 10.1038/s41467-022-35076-w. Nat Commun. 2022. PMID: 36463275 Free PMC article.
Genomic Characterization of Prostatic Basal Cell Carcinoma.
Low JY, Ko M, Hanratty B, Patel RA, Bhamidipati A, Heaphy CM, Sayar E, Lee JK, Li S, De Marzo AM, Nelson WG, Gupta A, Yegnasubramanian S, Ha G, Epstein JI, Haffner MC. Low JY, et al. Am J Pathol. 2023 Jan;193(1):4-10. doi: 10.1016/j.ajpath.2022.09.010. Epub 2022 Oct 26. Am J Pathol. 2023. PMID: 36309102 Free PMC article.
Patterns of structural variation define prostate cancer across disease states.
Zhou M, Ko M, Hoge AC, Luu K, Liu Y, Russell ML, Hannon WW, Zhang Z, Carrot-Zhang J, Beroukhim R, Van Allen EM, Choudhury AD, Nelson PS, Freedman ML, Taplin ME, Meyerson M, Viswanathan SR, Ha G. Zhou M, et al. JCI Insight. 2022 Sep 8;7(17):e161370. doi: 10.1172/jci.insight.161370. JCI Insight. 2022. PMID: 35943799 Free PMC article.
Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa.
Ahuno ST, Doebley AL, Ahearn TU, Yarney J, Titiloye N, Hamel N, Adjei E, Clegg-Lamptey JN, Edusei L, Awuah B, Song X, Vanderpuye V, Abubakar M, Duggan M, Stover DG, Nyarko K, Bartlett JMS, Aitpillah F, Ansong D, Gardner KL, Boateng FA, Bowcock AM, Caldas C, Foulkes WD, Wiafe S, Wiafe-Addai B, Garcia-Closas M, Kwarteng A, Ha G, Figueroa JD, Polak P; Ghana Breast Health Study Team. Ahuno ST, et al. NPJ Precis Oncol. 2021 Sep 17;5(1):83. doi: 10.1038/s41698-021-00219-7. NPJ Precis Oncol. 2021. PMID: 34535742 Free PMC article.