L30 NS089022/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2017	2
2018	4
2019	3
2020	2
2021	1
2022	1
2023	2
2025	0

1

MAPT mutations, tauopathy, and mechanisms of neurodegeneration.

Strang KH, Golde TE, Giasson BI. Strang KH, et al. Lab Invest. 2019 Jul;99(7):912-928. doi: 10.1038/s41374-019-0197-x. Epub 2019 Feb 11. Lab Invest. 2019. PMID: 30742061 Free PMC article. Review.

2

Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114.

Quintin S, Lloyd GM, Paterno G, Xia Y, Sorrentino Z, Bell BM, Gorion KM, Lee EB, Prokop S, Giasson BI. Quintin S, et al. J Biol Chem. 2023 Jul;299(7):104912. doi: 10.1016/j.jbc.2023.104912. Epub 2023 Jun 10. J Biol Chem. 2023. PMID: 37307916 Free PMC article.

3

Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice.

Lloyd GM, Sorrentino ZA, Quintin S, Gorion KM, Bell BM, Paterno G, Long B, Prokop S, Giasson BI. Lloyd GM, et al. Acta Neuropathol. 2022 Jun;143(6):663-685. doi: 10.1007/s00401-022-02425-4. Epub 2022 Apr 30. Acta Neuropathol. 2022. PMID: 35488930 Free PMC article.

4

Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies.

Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI. Strang KH, et al. J Biol Chem. 2018 Feb 16;293(7):2408-2421. doi: 10.1074/jbc.M117.815357. Epub 2017 Dec 19. J Biol Chem. 2018. PMID: 29259137 Free PMC article.

5

Phosphorylation of serine 305 in tau inhibits aggregation.

Strang KH, Sorrentino ZA, Riffe CJ, Gorion KM, Vijayaraghavan N, Golde TE, Giasson BI. Strang KH, et al. Neurosci Lett. 2019 Jan 23;692:187-192. doi: 10.1016/j.neulet.2018.11.011. Epub 2018 Nov 10. Neurosci Lett. 2019. PMID: 30423399 Free PMC article.

6

Physician perceptions about living organ donation in patients with Amyotrophic Lateral Sclerosis.

Ansari S, Bromberg MB, Gibson SB. Ansari S, et al. Clin Neurol Neurosurg. 2017 Sep;160:125-129. doi: 10.1016/j.clineuro.2017.07.004. Epub 2017 Jul 5. Clin Neurol Neurosurg. 2017. PMID: 28727995 Free PMC article.

7

Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions.

Sorrentino ZA, Vijayaraghavan N, Gorion KM, Riffe CJ, Strang KH, Caldwell J, Giasson BI. Sorrentino ZA, et al. J Biol Chem. 2018 Dec 7;293(49):18914-18932. doi: 10.1074/jbc.RA118.005603. Epub 2018 Oct 16. J Biol Chem. 2018. PMID: 30327435 Free PMC article.

8

Carboxy-terminal truncations of mouse α-synuclein alter aggregation and prion-like seeding.

Sorrentino ZA, Xia Y, Gorion KM, Hass E, Giasson BI. Sorrentino ZA, et al. FEBS Lett. 2020 Apr;594(8):1271-1283. doi: 10.1002/1873-3468.13728. Epub 2020 Jan 24. FEBS Lett. 2020. PMID: 31912891 Free PMC article.

9

Relationship of creatine kinase to body composition, disease state, and longevity in ALS.

Gibson SB, Kasarskis EJ, Hu N, Pulst SM, Mendiondo MS, Matthews DE, Mitsumoto H, Tandan R, Simmons Z, Kryscio RJ, Bromberg MB. Gibson SB, et al. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(7-8):473-7. doi: 10.3109/21678421.2015.1062516. Epub 2015 Aug 27. Amyotroph Lateral Scler Frontotemporal Degener. 2015. PMID: 26312548 Free PMC article.

10

Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis.

Lloyd GM, Long B, Quintin S, Sorrentino ZA, Gorion KM, Bell BM, Carrillo D, Sullivan P, Borchelt D, Giasson BI. Lloyd GM, et al. Acta Neuropathol Commun. 2023 Jul 23;11(1):119. doi: 10.1186/s40478-023-01623-9. Acta Neuropathol Commun. 2023. PMID: 37482615 Free PMC article.

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