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Page 1
Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells.
Georgescu T, Lyons D, Doslikova B, Garcia AP, Marston O, Burke LK, Chianese R, Lam BYH, Yeo GSH, Rochford JJ, Garfield AS, Heisler LK. Georgescu T, et al. Endocrinology. 2020 Apr 1;161(4):bqaa032. doi: 10.1210/endocr/bqaa032. Endocrinology. 2020. PMID: 32166324 Free PMC article.
Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression.
Wagner S, Brierley DI, Leeson-Payne A, Jiang W, Chianese R, Lam BYH, Dowsett GKC, Cristiano C, Lyons D, Reimann F, Gribble FM, Martinez de Morentin PB, Yeo GSH, Trapp S, Heisler LK. Wagner S, et al. Mol Metab. 2023 Feb;68:101665. doi: 10.1016/j.molmet.2022.101665. Epub 2022 Dec 30. Mol Metab. 2023. PMID: 36592795 Free PMC article.
Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake.
D'Agostino G, Lyons D, Cristiano C, Lettieri M, Olarte-Sanchez C, Burke LK, Greenwald-Yarnell M, Cansell C, Doslikova B, Georgescu T, Martinez de Morentin PB, Myers MG Jr, Rochford JJ, Heisler LK. D'Agostino G, et al. Cell Metab. 2018 Oct 2;28(4):619-630.e5. doi: 10.1016/j.cmet.2018.07.017. Epub 2018 Aug 23. Cell Metab. 2018. PMID: 30146485 Free PMC article.
5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding.
He Y, Cai X, Liu H, Conde KM, Xu P, Li Y, Wang C, Yu M, He Y, Liu H, Liang C, Yang T, Yang Y, Yu K, Wang J, Zheng R, Liu F, Sun Z, Heisler L, Wu Q, Tong Q, Zhu C, Shu G, Xu Y. He Y, et al. Mol Psychiatry. 2021 Dec;26(12):7211-7224. doi: 10.1038/s41380-021-01220-z. Epub 2021 Jul 21. Mol Psychiatry. 2021. PMID: 34290371 Free PMC article.
Lorcaserin improves glycemic control via a melanocortin neurocircuit.
Burke LK, Ogunnowo-Bada E, Georgescu T, Cristiano C, de Morentin PBM, Valencia Torres L, D'Agostino G, Riches C, Heeley N, Ruan Y, Rubinstein M, Low MJ, Myers MG, Rochford JJ, Evans ML, Heisler LK. Burke LK, et al. Mol Metab. 2017 Oct;6(10):1092-1102. doi: 10.1016/j.molmet.2017.07.004. Epub 2017 Jul 21. Mol Metab. 2017. PMID: 29031711 Free PMC article.
12 results