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Year Number of Results
2008 2
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2010 13
2011 24
2012 23
2013 18
2014 10
2015 10
2016 5
2017 1
2018 3
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2025 0

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107 results

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Page 1
BDDCS applied to over 900 drugs.
Benet LZ, Broccatelli F, Oprea TI. Benet LZ, et al. AAPS J. 2011 Dec;13(4):519-47. doi: 10.1208/s12248-011-9290-9. Epub 2011 Aug 5. AAPS J. 2011. PMID: 21818695 Free PMC article.
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, Eheim AL, Stoeckigt D, Maxcy KL, Cobert JM, Bachand J, Szekely BA, Mukherjee S, Sklar LA, Kotz JD, Clish CB, Sadreyev RI, Clemons PA, Janzer A, Schreiber SL, Scadden DT. Sykes DB, et al. Cell. 2016 Sep 22;167(1):171-186.e15. doi: 10.1016/j.cell.2016.08.057. Epub 2016 Sep 15. Cell. 2016. PMID: 27641501 Free PMC article.
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, Palmer M, Shamji AF, Wawer MJ, McManus O, Wu M, Zou B, Yu H, Golden JE, Schoenen FJ, Simeonov A, Jadhav A, Jackson MR, Pinkerton AB, Chung TD, Griffin PR, Cravatt BF, Hodder PS, Roush WR, Roberts E, Chung DH, Jonsson CB, Noah JW, Severson WE, Ananthan S, Edwards B, Oprea TI, Conn PJ, Hopkins CR, Wood MR, Stauffer SR, Emmitte KA; NIH Molecular Libraries Project Team. Schreiber SL, et al. Cell. 2015 Jun 4;161(6):1252-65. doi: 10.1016/j.cell.2015.05.023. Cell. 2015. PMID: 26046436 Free PMC article. Review.
Flow Cytometry: Impact on Early Drug Discovery.
Edwards BS, Sklar LA. Edwards BS, et al. J Biomol Screen. 2015 Jul;20(6):689-707. doi: 10.1177/1087057115578273. Epub 2015 Mar 24. J Biomol Screen. 2015. PMID: 25805180 Free PMC article. Review.
An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines.
de Souza A, Bittker JA, Lahr DL, Brudz S, Chatwin S, Oprea TI, Waller A, Yang JJ, Southall N, Guha R, Schürer SC, Vempati UD, Southern MR, Dawson ES, Clemons PA, Chung TD. de Souza A, et al. J Biomol Screen. 2014 Jun;19(5):614-27. doi: 10.1177/1087057113517139. Epub 2014 Jan 17. J Biomol Screen. 2014. PMID: 24441647 Free PMC article. Review.
Emerging trends in the discovery of natural product antibacterials.
Bologa CG, Ursu O, Oprea TI, Melançon CE 3rd, Tegos GP. Bologa CG, et al. Curr Opin Pharmacol. 2013 Oct;13(5):678-87. doi: 10.1016/j.coph.2013.07.002. Epub 2013 Jul 24. Curr Opin Pharmacol. 2013. PMID: 23890825 Free PMC article. Review.
Targeting efflux pumps to overcome antifungal drug resistance.
Holmes AR, Cardno TS, Strouse JJ, Ivnitski-Steele I, Keniya MV, Lackovic K, Monk BC, Sklar LA, Cannon RD. Holmes AR, et al. Future Med Chem. 2016 Aug;8(12):1485-501. doi: 10.4155/fmc-2016-0050. Epub 2016 Jul 27. Future Med Chem. 2016. PMID: 27463566 Free PMC article. Review.
Microbial efflux pump inhibition: tactics and strategies.
Tegos GP, Haynes M, Strouse JJ, Khan MM, Bologa CG, Oprea TI, Sklar LA. Tegos GP, et al. Curr Pharm Des. 2011;17(13):1291-302. doi: 10.2174/138161211795703726. Curr Pharm Des. 2011. PMID: 21470111 Free PMC article. Review.
107 results