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SOD1 is an essential H2S detoxifying enzyme.
Switzer CH, Kasamatsu S, Ihara H, Eaton P. Switzer CH, et al. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2205044120. doi: 10.1073/pnas.2205044120. Epub 2023 Jan 11. Proc Natl Acad Sci U S A. 2023. PMID: 36630448 Free PMC article.
Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation.
Stanley CP, Maghzal GJ, Ayer A, Talib J, Giltrap AM, Shengule S, Wolhuter K, Wang Y, Chadha P, Suarna C, Prysyazhna O, Scotcher J, Dunn LL, Prado FM, Nguyen N, Odiba JO, Baell JB, Stasch JP, Yamamoto Y, Di Mascio P, Eaton P, Payne RJ, Stocker R. Stanley CP, et al. Nature. 2019 Feb;566(7745):548-552. doi: 10.1038/s41586-019-0947-3. Epub 2019 Feb 13. Nature. 2019. PMID: 30760924
Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.
Simon JN, Vrellaku B, Monterisi S, Chu SM, Rawlings N, Lomas O, Marchal GA, Waithe D, Syeda F, Gajendragadkar PR, Jayaram R, Sayeed R, Channon KM, Fabritz L, Swietach P, Zaccolo M, Eaton P, Casadei B. Simon JN, et al. Circulation. 2021 Feb 2;143(5):449-465. doi: 10.1161/CIRCULATIONAHA.120.046761. Epub 2020 Nov 13. Circulation. 2021. PMID: 33185461 Free PMC article.
Enhanced Heart Failure in Redox-Dead Cys17Ser PKARIα Knock-In Mice.
Islam MMT, Tarnowski D, Zhang M, Trum M, Lebek S, Mustroph J, Daniel H, Moellencamp J, Pabel S, Sossalla S, El-Armouche A, Nikolaev VO, Shah AM, Eaton P, Maier LS, Sag CM, Wagner S. Islam MMT, et al. J Am Heart Assoc. 2021 Oct 5;10(19):e021985. doi: 10.1161/JAHA.121.021985. Epub 2021 Sep 29. J Am Heart Assoc. 2021. PMID: 34583520 Free PMC article.
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