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Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Luis TC, Barkas N, Carrelha J, Giustacchini A, Mazzi S, Norfo R, Wu B, Aliouat A, Guerrero JA, Rodriguez-Meira A, Bouriez-Jones T, Macaulay IC, Jasztal M, Zhu G, Ni H, Robson MJ, Blakely RD, Mead AJ, Nerlov C, Ghevaert C, Jacobsen SEW. Luis TC, et al. Nat Commun. 2023 Sep 28;14(1):6062. doi: 10.1038/s41467-023-41691-y. Nat Commun. 2023. PMID: 37770432 Free PMC article.
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Di Genua C, Valletta S, Buono M, Stoilova B, Sweeney C, Rodriguez-Meira A, Grover A, Drissen R, Meng Y, Beveridge R, Aboukhalil Z, Karamitros D, Belderbos ME, Bystrykh L, Thongjuea S, Vyas P, Nerlov C. Di Genua C, et al. Cancer Cell. 2020 May 11;37(5):690-704.e8. doi: 10.1016/j.ccell.2020.03.022. Epub 2020 Apr 23. Cancer Cell. 2020. PMID: 32330454 Free PMC article.