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Study partner-reported decline identifies cognitive decline and dementia risk.
Nosheny RL, Jin C, Neuhaus J, Insel PS, Mackin RS, Weiner MW; Alzheimer’s Disease Neuroimaging Initiative investigators. Nosheny RL, et al. Ann Clin Transl Neurol. 2019 Dec;6(12):2448-2459. doi: 10.1002/acn3.50938. Epub 2019 Nov 13. Ann Clin Transl Neurol. 2019. PMID: 31721455 Free PMC article.
METHODS: In 1048 older adults in the Alzheimer's Disease Neuroimaging Initiative (ADNI), we measured associations between Everyday Cognition Scale scores (ECog, self- and SP-reported versions) and (1) baseline and longitudinal change in neuropsychological test (NPT scores) …
METHODS: In 1048 older adults in the Alzheimer's Disease Neuroimaging Initiative (ADNI), we measured associations between Everyday Cognition …
Interregional causal influences of brain metabolic activity reveal the spread of aging effects during normal aging.
Di X, Wölfer M, Amend M, Wehrl H, Ionescu TM, Pichler BJ, Biswal BB; Alzheimer's Disease Neuroimaging Initiative. Di X, et al. Hum Brain Mapp. 2019 Nov 1;40(16):4657-4668. doi: 10.1002/hbm.24728. Epub 2019 Aug 7. Hum Brain Mapp. 2019. PMID: 31389641 Free PMC article.
The current data demonstrated interregional spreads of aging on metabolic activity at the scale of a year, and have identified key brain regions in the aging process that have strong influences over other regions....
The current data demonstrated interregional spreads of aging on metabolic activity at the scale of a year, and have identified key br …