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Re-engineering of CYP2C9 to probe acid-base substrate selectivity.
Drug Metab Dispos. 2008 Oct;36(10):1992-7. doi: 10.1124/dmd.108.022186. Epub 2008 Jul 7.
Drug Metab Dispos. 2008.
PMID: 18606741
Free PMC article.
The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.
Roberts AG, Yang J, Halpert JR, Nelson SD, Thummel KT, Atkins WM.
Roberts AG, et al.
Biochemistry. 2011 Dec 20;50(50):10804-18. doi: 10.1021/bi200924t. Epub 2011 Nov 22.
Biochemistry. 2011.
PMID: 21992114
Free PMC article.
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