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Page 1
Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer.
Bell HN, Huber AK, Singhal R, Korimerla N, Rebernick RJ, Kumar R, El-Derany MO, Sajjakulnukit P, Das NK, Kerk SA, Solanki S, James JG, Kim D, Zhang L, Chen B, Mehra R, Frankel TL, Győrffy B, Fearon ER, Pasca di Magliano M, Gonzalez FJ, Banerjee R, Wahl DR, Lyssiotis CA, Green M, Shah YM. Bell HN, et al. Cell Metab. 2023 Jan 3;35(1):134-149.e6. doi: 10.1016/j.cmet.2022.11.013. Epub 2022 Dec 16. Cell Metab. 2023. PMID: 36528023 Free PMC article.
Opposing diet, microbiome, and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host.
Pereira GV, Boudaud M, Wolter M, Alexander C, De Sciscio A, Grant ET, Trindade BC, Pudlo NA, Singh S, Campbell A, Shan M, Zhang L, Yang Q, Willieme S, Kim K, Denike-Duval T, Fuentes J, Bleich A, Schmidt TM, Kennedy L, Lyssiotis CA, Chen GY, Eaton KA, Desai MS, Martens EC. Pereira GV, et al. Cell Host Microbe. 2024 Apr 10;32(4):527-542.e9. doi: 10.1016/j.chom.2024.03.001. Epub 2024 Mar 20. Cell Host Microbe. 2024. PMID: 38513656 Free article.
Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation.
Seike K, Kiledal A, Fujiwara H, Henig I, Burgos da Silva M, van den Brink MRM, Hein R, Hoostal M, Liu C, Oravecz-Wilson K, Lauder E, Li L, Sun Y, Schmidt TM, Shah YM, Jenq RR, Dick G, Reddy P. Seike K, et al. Immunity. 2023 Feb 14;56(2):353-368.e6. doi: 10.1016/j.immuni.2023.01.007. Epub 2023 Feb 2. Immunity. 2023. PMID: 36736321 Free PMC article.
H2S preconditioning induces long-lived perturbations in O2 metabolism.
Hanna DA, Diessl J, Guha A, Kumar R, Andren A, Lyssiotis C, Banerjee R. Hanna DA, et al. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2319473121. doi: 10.1073/pnas.2319473121. Epub 2024 Mar 13. Proc Natl Acad Sci U S A. 2024. PMID: 38478695 Free PMC article.
Feasibility of a dietary intervention to modify gut microbial metabolism in patients with hematopoietic stem cell transplantation.
Riwes MM, Golob JL, Magenau J, Shan M, Dick G, Braun T, Schmidt TM, Pawarode A, Anand S, Ghosh M, Maciejewski J, King D, Choi S, Yanik G, Geer M, Hillman E, Lyssiotis CA, Tewari M, Reddy P. Riwes MM, et al. Nat Med. 2023 Nov;29(11):2805-2813. doi: 10.1038/s41591-023-02587-y. Epub 2023 Oct 19. Nat Med. 2023. PMID: 37857710 Free PMC article. Clinical Trial.
Unravelling specific diet and gut microbial contributions to inflammatory bowel disease.
Pereira GV, Boudaud M, Wolter M, Alexander C, De Sciscio A, Grant ET, Trindade BC, Pudlo NA, Singh S, Campbell A, Shan M, Zhang L, Willieme S, Kim K, Denike-Duval T, Bleich A, Schmidt TM, Kennedy L, Lyssiotis CA, Chen GY, Eaton KA, Desai MS, Martens EC. Pereira GV, et al. Res Sq [Preprint]. 2023 Mar 13:rs.3.rs-2518251. doi: 10.21203/rs.3.rs-2518251/v1. Res Sq. 2023. PMID: 36993463 Free PMC article. Preprint.
Rearrangement of T Cell genome architecture regulates GVHD.
Sun Y, Dotson GA, Muir LA, Ronquist S, Oravecz-Wilson K, Peltier D, Seike K, Li L, Meixner W, Rajapakse I, Reddy P. Sun Y, et al. iScience. 2022 Aug 6;25(9):104846. doi: 10.1016/j.isci.2022.104846. eCollection 2022 Sep 16. iScience. 2022. PMID: 36043052 Free PMC article.
Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
Fujiwara H, Seike K, Brooks MD, Mathew AV, Kovalenko I, Pal A, Lee HJ, Peltier D, Kim S, Liu C, Oravecz-Wilson K, Li L, Sun Y, Byun J, Maeda Y, Wicha MS, Saunders TL, Rehemtulla A, Lyssiotis CA, Pennathur S, Reddy P. Fujiwara H, et al. Nat Immunol. 2021 Nov;22(11):1440-1451. doi: 10.1038/s41590-021-01048-3. Epub 2021 Oct 22. Nat Immunol. 2021. PMID: 34686860 Free PMC article.
18 results