Abstract
Skin ulceration is a major source of morbidity and is often difficult to manage. Ulcers caused by an inflammatory cause or microvascular occlusion are particularly challenging in terms of diagnosis and treatment. The management of such ulcers requires careful assessment of associated systemic conditions and a thorough analysis of the ulcer's clinical and histologic findings. In this article, the authors discuss several examples of inflammatory ulcers and the approach to the diagnosis and treatment of these ulcers.
Copyright © 2010 Elsevier Inc. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Biopsy, Needle
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Calciphylaxis / complications*
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Calciphylaxis / pathology
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Chronic Disease
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Combined Modality Therapy
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Embolism, Cholesterol / complications*
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Embolism, Cholesterol / pathology
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Female
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Humans
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Immunohistochemistry
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Inflammation / complications
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Inflammation / pathology
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Male
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Necrosis / complications
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Necrosis / pathology
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Pain Measurement
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Prognosis
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Severity of Illness Index
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Skin Care / methods
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Skin Ulcer / etiology*
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Skin Ulcer / pathology
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Skin Ulcer / therapy
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Vasculitis / complications*
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Vasculitis / pathology
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Wound Healing / physiology