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Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset.
Li Y, Yen D, Hendrix RD, Gordon BA, Dlamini S, Barthélemy NR, Aschenbrenner AJ, Henson RL, Herries EM, Volluz K, Kirmess K, Eastwood S, Meyer M, Heller M, Jarrett L, McDade E, Holtzman DM, Benzinger TLS, Morris JC, Bateman RJ, Xiong C, Schindler SE. Li Y, et al. Ann Neurol. 2024 May;95(5):951-965. doi: 10.1002/ana.26891. Epub 2024 Feb 24. Ann Neurol. 2024. PMID: 38400792
Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease.
Panyard DJ, McKetney J, Deming YK, Morrow AR, Ennis GE, Jonaitis EM, Van Hulle CA, Yang C, Sung YJ, Ali M, Kollmorgen G, Suridjan I, Bayfield A, Bendlin BB, Zetterberg H, Blennow K, Cruchaga C, Carlsson CM, Johnson SC, Asthana S, Coon JJ, Engelman CD. Panyard DJ, et al. Alzheimers Dement. 2023 Dec;19(12):5447-5470. doi: 10.1002/alz.13130. Epub 2023 May 22. Alzheimers Dement. 2023. PMID: 37218097 Free PMC article.
Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients.
Brier MR, Schindler SE, Salter A, Perantie D, Shelley N, Judge B, Keefe S, Kirmess KM, Verghese PB, Yarasheski KE, Venkatesh V, Raji CA, Gordon BA, Bateman RJ, Morris JC, Naismith RT, Holtzman DM, Benzinger TLS, Cross AH. Brier MR, et al. Ann Neurol. 2024 Sep;96(3):453-459. doi: 10.1002/ana.27027. Epub 2024 Jul 4. Ann Neurol. 2024. PMID: 38963256
Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.
Panyard DJ, Reus LM, Ali M, Liu J, Deming YK, Lu Q, Kollmorgen G, Carboni M, Wild N, Visser PJ, Bertram L, Zetterberg H, Blennow K, Gobom J, Western D, Sung YJ, Carlsson CM, Johnson SC, Asthana S, Cruchaga C, Tijms BM, Engelman CD, Snyder MP. Panyard DJ, et al. Alzheimers Dement. 2024 Jul;20(7):5044-5053. doi: 10.1002/alz.13848. Epub 2024 May 29. Alzheimers Dement. 2024. PMID: 38809917 Free PMC article.