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Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages.
Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. Covarrubias AJ, et al. Nat Metab. 2020 Nov;2(11):1265-1283. doi: 10.1038/s42255-020-00305-3. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199924 Free PMC article.
Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network.
Vasunilashorn SM, Lunardi N, Newman JC, Crosby G, Acker L, Abel T, Bhatnagar S, Cunningham C, de Cabo R, Dugan L, Hippensteel JA, Ishizawa Y, Lahiri S, Marcantonio ER, Xie Z, Inouye SK, Terrando N, Eckenhoff RG; NIDUS Delirium Network. Vasunilashorn SM, et al. Alzheimers Dement. 2023 May;19(5):2150-2174. doi: 10.1002/alz.12941. Epub 2023 Feb 17. Alzheimers Dement. 2023. PMID: 36799408 Free PMC article. Review.
Interpreting Geroscience-Guided Biomarker Studies.
Bauer SR, Newman JC. Bauer SR, et al. JAMA Intern Med. 2022 Mar 1;182(3):300-302. doi: 10.1001/jamainternmed.2021.7812. JAMA Intern Med. 2022. PMID: 35040910 Free PMC article. No abstract available.
A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging.
Nomura M, Murad NF, Madhavan SS, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC. Nomura M, et al. bioRxiv [Preprint]. 2023 Dec 4:2023.12.01.569598. doi: 10.1101/2023.12.01.569598. bioRxiv. 2023. Update in: Aging Biol. 2024;2:20240038. doi: 10.59368/agingbio.20240038 PMID: 38106160 Free PMC article. Updated. Preprint.