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Interleukin-21 promotes Type-1 activation and cytotoxicity of CD56dimCD16bright natural killer cells during kidney allograft antibody-mediated rejection showing a new link between adaptive and innate humoral allo-immunity.
Bailly E, Macedo C, Ossart J, Louis K, Gu X, Ramaswami B, Bentlejewski C, Zeevi A, Randhawa P, Lefaucheur C, Metes D. Bailly E, et al. Kidney Int. 2023 Oct;104(4):707-723. doi: 10.1016/j.kint.2023.04.024. Epub 2023 May 21. Kidney Int. 2023. PMID: 37220805 Free PMC article.
Coordinated Circulating T Follicular Helper and Activated B Cell Responses Underlie the Onset of Antibody-Mediated Rejection in Kidney Transplantation.
Louis K, Macedo C, Bailly E, Lau L, Ramaswami B, Marrari M, Landsittel D, Chang A, Chandran U, Fadakar P, Yamada M, Chalasani G, Randhawa P, Zeevi A, Singh H, Lefaucheur C, Metes D. Louis K, et al. J Am Soc Nephrol. 2020 Oct;31(10):2457-2474. doi: 10.1681/ASN.2020030320. Epub 2020 Jul 28. J Am Soc Nephrol. 2020. PMID: 32723838 Free PMC article.
Impact of Induction Therapy on Circulating T Follicular Helper Cells and Subsequent Donor-Specific Antibody Formation After Kidney Transplant.
Macedo C, Hadi K, Walters J, Elinoff B, Marrari M, Zeevi A, Ramaswami B, Chalasani G, Landsittel D, Shields A, Alloway R, Lakkis FG, Woodle ES, Metes D. Macedo C, et al. Kidney Int Rep. 2018 Dec 8;4(3):455-469. doi: 10.1016/j.ekir.2018.11.020. eCollection 2019 Mar. Kidney Int Rep. 2018. PMID: 30899873 Free PMC article.