R01 AI162633/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	2
2022	5
2023	6
2024	7

1

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.

Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S. Menolfi D, et al. Nat Commun. 2023 Jun 19;14(1):3618. doi: 10.1038/s41467-023-39332-5. Nat Commun. 2023. PMID: 37336885 Free PMC article.

2

SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma.

Abdelrazak Morsy MH, Lilienthal I, Lord M, Merrien M, Wasik AM, Sureda-Gómez M, Amador V, Johansson HJ, Lehtiö J, Garcia-Torre B, Martin-Subero JI, Tsesmetzis N, Tao S, Schinazi RF, Kim B, Sorteberg AL, Wickström M, Sheppard D, Rassidakis GZ, Taylor IA, Christensson B, Campo E, Herold N, Sander B. Abdelrazak Morsy MH, et al. Blood. 2024 May 9;143(19):1953-1964. doi: 10.1182/blood.2023022241. Epub 2024 Jan 18. Blood. 2024. PMID: 38237141 Free PMC article.

3

Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cells.

Valeri E, Unali G, Piras F, Abou-Alezz M, Pais G, Benedicenti F, Lidonnici MR, Cuccovillo I, Castiglioni I, Arévalo S, Spinozzi G, Merelli I, Behrendt R, Oo A, Kim B, Landau NR, Ferrari G, Montini E, Kajaste-Rudnitski A. Valeri E, et al. Mol Ther. 2024 Jan 3;32(1):124-139. doi: 10.1016/j.ymthe.2023.11.020. Epub 2023 Nov 20. Mol Ther. 2024. PMID: 37990494 Free article.

4

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction, and cellular dNTP levels.

Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Schüssler M, et al. mBio. 2023 Oct 31;14(5):e0225223. doi: 10.1128/mbio.02252-23. Epub 2023 Oct 6. mBio. 2023. PMID: 37800914 Free PMC article.

5

SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks.

Kapoor-Vazirani P, Rath SK, Liu X, Shu Z, Bowen NE, Chen Y, Haji-Seyed-Javadi R, Daddacha W, Minten EV, Danelia D, Farchi D, Duong DM, Seyfried NT, Deng X, Ortlund EA, Kim B, Yu DS. Kapoor-Vazirani P, et al. Nat Commun. 2022 Nov 7;13(1):6707. doi: 10.1038/s41467-022-34578-x. Nat Commun. 2022. PMID: 36344525 Free PMC article.

6

Mechanistic Interplay between HIV-1 Reverse Transcriptase Enzyme Kinetics and Host SAMHD1 Protein: Viral Myeloid-Cell Tropism and Genomic Mutagenesis.

Bowen NE, Oo A, Kim B. Bowen NE, et al. Viruses. 2022 Jul 26;14(8):1622. doi: 10.3390/v14081622. Viruses. 2022. PMID: 35893688 Free PMC article. Review.

7

NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome.

Sobh A, Encinas E, Patel A, Surapaneni G, Bonilla E, Kaestner C, Poullard J, Clerio M, Vasan K, Freeman T, Lv D, Dupéré-Richer D, Riva A, Barwick BG, Zhou D, Boise LH, Mitsiades CS, Kim B, Bennett RL, Chandel NS, Licht JD. Sobh A, et al. Blood. 2024 Jul 18;144(3):283-295. doi: 10.1182/blood.2023022859. Blood. 2024. PMID: 38598835

8

SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients.

Daddacha W, Monroe D, Schlafstein AJ, Withers AE, Thompson EB, Danelia D, Luong NC, Sesay F, Rath SK, Usoro ER, Essien ME, Jung AT, Jiang JG, Hu J, Mahboubi B, Williams A, Steinbeck JE, Yang X, Buchwald ZS, Dynan WS, Switchenko JM, Kim B, Khan MK, Jaye DL, Yu DS. Daddacha W, et al. NAR Cancer. 2024 Feb 24;6(1):zcae007. doi: 10.1093/narcan/zcae007. eCollection 2024 Mar. NAR Cancer. 2024. PMID: 38406263 Free PMC article.

9

Biochemical functions and structure of Caenorhabditis elegans ZK177.8 protein: Aicardi-Goutières syndrome SAMHD1 dNTPase ortholog.

Maehigashi T, Lim C, Wade LR, Bowen NE, Knecht KM, Alvarez NN, Kelly WG, Schinazi RF, Kim DH, Xiong Y, Kim B. Maehigashi T, et al. J Biol Chem. 2023 Sep;299(9):105148. doi: 10.1016/j.jbc.2023.105148. Epub 2023 Aug 9. J Biol Chem. 2023. PMID: 37567474 Free PMC article.

10

SAMHD1 Promotes the Antiretroviral Adaptive Immune Response in Mice Exposed to Lipopolysaccharide.

Barrett B, Nguyen DH, Xu J, Guo K, Shetty S, Jones ST, Mickens KL, Shepard C, Roers A, Behrendt R, Wu L, Kim B, Santiago ML. Barrett B, et al. J Immunol. 2022 Jan 15;208(2):444-453. doi: 10.4049/jimmunol.2001389. Epub 2021 Dec 10. J Immunol. 2022. PMID: 34893529 Free PMC article.

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