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Rationally-defined microbial consortia suppress multidrug-resistant proinflammatory Enterobacteriaceae via ecological control.
Honda K, Furuichi M, Kawaguchi T, Pust MM, Yasuma-Mitobe K, Plichta D, Hasegawa N, Ohya T, Bhattarai S, Sasajima S, Yoshimasa A, Tuganbaev T, Yaginuma M, Ueda M, Okahashi N, Amafuji K, Kiridooshi Y, Sugita K, Stražar M, Skelly A, Suda W, Hattori M, Nakamoto N, Caballero S, Norman J, Olle B, Tanoue T, Arita M, Bucci V, Atarashi K, Xavier R. Honda K, et al. Res Sq [Preprint]. 2023 Oct 23:rs.3.rs-3462622. doi: 10.21203/rs.3.rs-3462622/v1. Res Sq. 2023. Update in: Nature. 2024 Sep;633(8031):878-886. doi: 10.1038/s41586-024-07960-6 PMID: 37961431 Free PMC article. Updated. Preprint.
Akkermansia muciniphila phospholipid induces homeostatic immune responses.
Bae M, Cassilly CD, Liu X, Park SM, Tusi BK, Chen X, Kwon J, Filipčík P, Bolze AS, Liu Z, Vlamakis H, Graham DB, Buhrlage SJ, Xavier RJ, Clardy J. Bae M, et al. Nature. 2022 Aug;608(7921):168-173. doi: 10.1038/s41586-022-04985-7. Epub 2022 Jul 27. Nature. 2022. PMID: 35896748 Free PMC article.
Commensal consortia decolonize Enterobacteriaceae via ecological control.
Furuichi M, Kawaguchi T, Pust MM, Yasuma-Mitobe K, Plichta DR, Hasegawa N, Ohya T, Bhattarai SK, Sasajima S, Aoto Y, Tuganbaev T, Yaginuma M, Ueda M, Okahashi N, Amafuji K, Kiridoshi Y, Sugita K, Stražar M, Avila-Pacheco J, Pierce K, Clish CB, Skelly AN, Hattori M, Nakamoto N, Caballero S, Norman JM, Olle B, Tanoue T, Suda W, Arita M, Bucci V, Atarashi K, Xavier RJ, Honda K. Furuichi M, et al. Nature. 2024 Sep;633(8031):878-886. doi: 10.1038/s41586-024-07960-6. Epub 2024 Sep 18. Nature. 2024. PMID: 39294375 Free PMC article.
Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course.
Schirmer M, Stražar M, Avila-Pacheco J, Rojas-Tapias DF, Brown EM, Temple E, Deik A, Bullock K, Jeanfavre S, Pierce K, Jin S, Invernizzi R, Pust MM, Costliow Z, Mack DR, Griffiths AM, Walters T, Boyle BM, Kugathasan S, Vlamakis H, Hyams J, Denson L, Clish CB, Xavier RJ. Schirmer M, et al. Cell Host Microbe. 2024 Feb 14;32(2):209-226.e7. doi: 10.1016/j.chom.2023.12.013. Epub 2024 Jan 11. Cell Host Microbe. 2024. PMID: 38215740
Discovering functional small molecules in the gut microbiome.
Seyedsayamdost MR, Clardy J. Seyedsayamdost MR, et al. Curr Opin Chem Biol. 2023 Aug;75:102309. doi: 10.1016/j.cbpa.2023.102309. Epub 2023 May 8. Curr Opin Chem Biol. 2023. PMID: 37163788 Free PMC article. Review.
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