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Deciphering molecular mechanisms stabilizing the reovirus-binding complex.
Dos Santos Natividade R, Koehler M, Gomes PSFC, Simpson JD, Smith SC, Gomes DEB, de Lhoneux J, Yang J, Ray A, Dermody TS, Bernardi RC, Ogden KM, Alsteens D. Dos Santos Natividade R, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2220741120. doi: 10.1073/pnas.2220741120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186838 Free PMC article.
NgR1 binding to reovirus reveals an unusual bivalent interaction and a new viral attachment protein.
Sutherland DM, Strebl M, Koehler M, Welsh OL, Yu X, Hu L, Dos Santos Natividade R, Knowlton JJ, Taylor GM, Moreno RA, Wörz P, Lonergan ZR, Aravamudhan P, Guzman-Cardozo C, Kour S, Pandey UB, Alsteens D, Wang Z, Prasad BVV, Stehle T, Dermody TS. Sutherland DM, et al. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2219404120. doi: 10.1073/pnas.2219404120. Epub 2023 Jun 5. Proc Natl Acad Sci U S A. 2023. PMID: 37276413 Free PMC article.
Viral capsid structural assembly governs the reovirus binding interface to NgR1.
Dos Santos Natividade R, Dumitru AC, Nicoli A, Strebl M, Sutherland DM, Welsh OL, Ghulam M, Stehle T, Dermody TS, Di Pizio A, Koehler M, Alsteens D. Dos Santos Natividade R, et al. Nanoscale Horiz. 2024 Oct 21;9(11):1925-1937. doi: 10.1039/d4nh00315b. Nanoscale Horiz. 2024. PMID: 39347978 Free PMC article.