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Year Number of Results
2018 6
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2020 2
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2022 4
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2024 1

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19 results

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Page 1
Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis.
Shkhyan R, Flynn C, Lamoure E, Sarkar A, Van Handel B, Li J, York J, Banks N, Van der Horst R, Liu NQ, Lee S, Bajaj P, Vadivel K, Harn HI, Tassey J, Lozito T, Lieberman JR, Chuong CM, Hurtig MS, Evseenko D. Shkhyan R, et al. Sci Transl Med. 2023 Mar 22;15(688):eabq2395. doi: 10.1126/scitranslmed.abq2395. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947594 Free PMC article.
STAT3 promotes a youthful epigenetic state in articular chondrocytes.
Sarkar A, Liu NQ, Magallanes J, Tassey J, Lee S, Shkhyan R, Lee Y, Lu J, Ouyang Y, Tang H, Bian F, Tao L, Segil N, Ernst J, Lyons K, Horvath S, Evseenko D. Sarkar A, et al. Aging Cell. 2023 Feb;22(2):e13773. doi: 10.1111/acel.13773. Epub 2023 Jan 13. Aging Cell. 2023. PMID: 36638270 Free PMC article.
CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance.
Zhao G, Huang BL, Rigueur D, Wang W, Bhoot C, Charles KR, Baek J, Mohan S, Jiang J, Lyons KM. Zhao G, et al. J Bone Miner Res. 2018 Jun;33(6):1076-1089. doi: 10.1002/jbmr.3394. Epub 2018 Mar 5. J Bone Miner Res. 2018. PMID: 29351359 Free PMC article.
Modulation of Hedgehog Signaling by Kappa Opioids to Attenuate Osteoarthritis.
Weber AE, Jalali O, Limfat S, Shkhyan R, Van Der Horst R, Lee S, Lin Y, Li L, Mayer EN, Wang L, Liu NQ, Petrigliano FA, Lieberman JR, Evseenko D. Weber AE, et al. Arthritis Rheumatol. 2020 Aug;72(8):1278-1288. doi: 10.1002/art.41250. Epub 2020 Jun 24. Arthritis Rheumatol. 2020. PMID: 32249508 Free PMC article.
Molecular characterization of physis tissue by RNA sequencing.
Paradise CR, Galeano-Garces C, Galeano-Garces D, Dudakovic A, Milbrandt TA, Saris DBF, Krych AJ, Karperien M, Ferguson GB, Evseenko D, Riester SM, van Wijnen AJ, Larson AN. Paradise CR, et al. Gene. 2018 Aug 20;668:87-96. doi: 10.1016/j.gene.2018.05.034. Epub 2018 May 25. Gene. 2018. PMID: 29775757 Free PMC article.
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair.
Shkhyan R, Van Handel B, Bogdanov J, Lee S, Yu Y, Scheinberg M, Banks NW, Limfat S, Chernostrik A, Franciozi CE, Alam MP, John V, Wu L, Ferguson GB, Nsair A, Petrigliano FA, Vangsness CT, Vadivel K, Bajaj P, Wang L, Liu NQ, Evseenko D. Shkhyan R, et al. Ann Rheum Dis. 2018 May;77(5):760-769. doi: 10.1136/annrheumdis-2017-212037. Epub 2018 Feb 7. Ann Rheum Dis. 2018. PMID: 29436471 Free PMC article.
gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes.
Liu NQ, Lin Y, Li L, Lu J, Geng D, Zhang J, Jashashvili T, Buser Z, Magallanes J, Tassey J, Shkhyan R, Sarkar A, Lopez N, Lee S, Lee Y, Wang L, Petrigliano FA, Van Handel B, Lyons K, Evseenko D. Liu NQ, et al. Commun Biol. 2022 Jan 17;5(1):64. doi: 10.1038/s42003-021-02944-y. Commun Biol. 2022. PMID: 35039652 Free PMC article.
19 results