R01 CA068377/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1998	2
2000	2
2001	1
2003	1
2004	1
2006	2
2007	2
2009	4
2010	4
2011	4
2012	2
2013	1
2014	4
2015	1
2016	1
2017	1
2018	1
2019	1
2020	3
2021	1
2022	4
2023	1
2025	0

1

Advancing targeted protein degradation for cancer therapy.

Dale B, Cheng M, Park KS, Kaniskan HÜ, Xiong Y, Jin J. Dale B, et al. Nat Rev Cancer. 2021 Oct;21(10):638-654. doi: 10.1038/s41568-021-00365-x. Epub 2021 Jun 15. Nat Rev Cancer. 2021. PMID: 34131295 Free PMC article. Review.

2

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y. Xu W, et al. Cancer Cell. 2011 Jan 18;19(1):17-30. doi: 10.1016/j.ccr.2010.12.014. Cancer Cell. 2011. PMID: 21251613 Free PMC article.

3

An MDM2 degrader for treatment of acute leukemias.

Marcellino BK, Yang X, Ümit Kaniskan H, Brady C, Chen H, Chen K, Qiu X, Clementelli C, Herschbein L, Li Z, Elghaity-Beckley S, Arandela J, Kelly B, Hoffman R, Liu J, Xiong Y, Jin J, Shih AH. Marcellino BK, et al. Leukemia. 2023 Feb;37(2):370-378. doi: 10.1038/s41375-022-01735-6. Epub 2022 Oct 29. Leukemia. 2023. PMID: 36309559 Free PMC article.

4

Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates.

Ye D, Guan KL, Xiong Y. Ye D, et al. Trends Cancer. 2018 Feb;4(2):151-165. doi: 10.1016/j.trecan.2017.12.005. Epub 2018 Jan 5. Trends Cancer. 2018. PMID: 29458964 Free PMC article. Review.

5

Structure of CRL7^FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation.

Hopf LVM, Baek K, Klügel M, von Gronau S, Xiong Y, Schulman BA. Hopf LVM, et al. Nat Struct Mol Biol. 2022 Sep;29(9):854-862. doi: 10.1038/s41594-022-00815-6. Epub 2022 Aug 18. Nat Struct Mol Biol. 2022. PMID: 35982156 Free PMC article.

6

Alterations of metabolic genes and metabolites in cancer.

Oermann EK, Wu J, Guan KL, Xiong Y. Oermann EK, et al. Semin Cell Dev Biol. 2012 Jun;23(4):370-80. doi: 10.1016/j.semcdb.2012.01.013. Epub 2012 Jan 28. Semin Cell Dev Biol. 2012. PMID: 22306135 Free PMC article. Review.

7

CRL4^DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development.

Han XR, Sasaki N, Jackson SC, Wang P, Li Z, Smith MD, Xie L, Chen X, Zhang Y, Marzluff WF, Xiong Y. Han XR, et al. Sci Adv. 2020 Dec 18;6(51):eabd6078. doi: 10.1126/sciadv.abd6078. Print 2020 Dec. Sci Adv. 2020. PMID: 33355139 Free PMC article.

8

Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.

Lin R, Tao R, Gao X, Li T, Zhou X, Guan KL, Xiong Y, Lei QY. Lin R, et al. Mol Cell. 2013 Aug 22;51(4):506-518. doi: 10.1016/j.molcel.2013.07.002. Epub 2013 Aug 8. Mol Cell. 2013. PMID: 23932781 Free PMC article.

9

Chromatin regulation by CRL4 E3 ubiquitin ligases: CUL4B targets WDR5 ubiquitylation in the nucleus.

Nakagawa T, Xiong Y. Nakagawa T, et al. Cell Cycle. 2011 Dec 15;10(24):4197-8. doi: 10.4161/cc.10.24.18407. Epub 2011 Dec 15. Cell Cycle. 2011. PMID: 22107965 Free PMC article. No abstract available.

10

Exploring Degradation of Mutant and Wild-Type Epidermal Growth Factor Receptors Induced by Proteolysis-Targeting Chimeras.

Yu X, Cheng M, Lu K, Shen Y, Zhong Y, Liu J, Xiong Y, Jin J. Yu X, et al. J Med Chem. 2022 Jun 23;65(12):8416-8443. doi: 10.1021/acs.jmedchem.2c00345. Epub 2022 Jun 8. J Med Chem. 2022. PMID: 35675209 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Results by year

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

41 results

Results by year

Search Page

Filters

My Custom Filters

Results by year

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

41 results

Results by year