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Page 1
Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.
Ansa-Addo EA, Thaxton J, Hong F, Wu BX, Zhang Y, Fugle CW, Metelli A, Riesenberg B, Williams K, Gewirth DT, Chiosis G, Liu B, Li Z. Ansa-Addo EA, et al. Curr Top Med Chem. 2016;16(25):2765-78. doi: 10.2174/1568026616666160413141613. Curr Top Med Chem. 2016. PMID: 27072698 Free PMC article. Review.
Exploring the Functional Complementation between Grp94 and Hsp90.
Maharaj KA, Que NL, Hong F, Huck JD, Gill SK, Wu S, Li Z, Gewirth DT. Maharaj KA, et al. PLoS One. 2016 Nov 8;11(11):e0166271. doi: 10.1371/journal.pone.0166271. eCollection 2016. PLoS One. 2016. PMID: 27824935 Free PMC article.
Characterization of the Grp94/OS-9 chaperone-lectin complex.
Seidler PM, Shinsky SA, Hong F, Li Z, Cosgrove MS, Gewirth DT. Seidler PM, et al. J Mol Biol. 2014 Oct 23;426(21):3590-605. doi: 10.1016/j.jmb.2014.08.024. Epub 2014 Sep 3. J Mol Biol. 2014. PMID: 25193139 Free PMC article.
Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94.
Patel HJ, Patel PD, Ochiana SO, Yan P, Sun W, Patel MR, Shah SK, Tramentozzi E, Brooks J, Bolaender A, Shrestha L, Stephani R, Finotti P, Leifer C, Li Z, Gewirth DT, Taldone T, Chiosis G. Patel HJ, et al. J Med Chem. 2015 May 14;58(9):3922-43. doi: 10.1021/acs.jmedchem.5b00197. Epub 2015 Apr 22. J Med Chem. 2015. PMID: 25901531 Free PMC article.
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