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Targeting sphingosine-1-phosphate receptors in cancer.
Watters RJ, Wang HG, Sung SS, Loughran TP, Liu X. Watters RJ, et al. Anticancer Agents Med Chem. 2011 Nov;11(9):810-7. doi: 10.2174/187152011797655041. Anticancer Agents Med Chem. 2011. PMID: 21707490 Free PMC article. Review.
Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia.
Liao A, Broeg K, Fox T, Tan SF, Watters R, Shah MV, Zhang LQ, Li Y, Ryland L, Yang J, Aliaga C, Dewey A, Rogers A, Loughran K, Hirsch L, Jarbadan NR, Baab KT, Liao J, Wang HG, Kester M, Desai D, Amin S, Loughran TP Jr, Liu X. Liao A, et al. Blood. 2011 Sep 8;118(10):2793-800. doi: 10.1182/blood-2011-01-331447. Epub 2011 Jul 18. Blood. 2011. PMID: 21768294 Free PMC article.
Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation.
Doi K, Li R, Sung SS, Wu H, Liu Y, Manieri W, Krishnegowda G, Awwad A, Dewey A, Liu X, Amin S, Cheng C, Qin Y, Schonbrunn E, Daughdrill G, Loughran TP Jr, Sebti S, Wang HG. Doi K, et al. J Biol Chem. 2012 Mar 23;287(13):10224-10235. doi: 10.1074/jbc.M111.334532. Epub 2012 Feb 6. J Biol Chem. 2012. PMID: 22311987 Free PMC article.
Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: results of a bone marrow failure consortium study.
Nyland SB, Krissinger DJ, Clemente MJ, Irby RB, Baab KT, Jarbadan NR, Sokol L, Schaefer E, Liao J, Cuthbertson D, Epling-Burnette P, Paquette R, List AF, Maciejewski JP, Loughran TP Jr. Nyland SB, et al. Leuk Res. 2012 May;36(5):581-7. doi: 10.1016/j.leukres.2012.02.001. Epub 2012 Mar 2. Leuk Res. 2012. PMID: 22386729 Free PMC article.