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CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies.
Kohrt HE, Houot R, Goldstein MJ, Weiskopf K, Alizadeh AA, Brody J, Müller A, Pachynski R, Czerwinski D, Coutre S, Chao MP, Chen L, Tedder TF, Levy R. Kohrt HE, et al. Blood. 2011 Feb 24;117(8):2423-32. doi: 10.1182/blood-2010-08-301945. Epub 2010 Dec 30. Blood. 2011. Retraction in: Blood. 2019 Aug 15;134(7):658. doi: 10.1182/blood.2019002416 PMID: 21193697 Free PMC article. Retracted.
Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer.
Kohrt HE, Houot R, Weiskopf K, Goldstein MJ, Scheeren F, Czerwinski D, Colevas AD, Weng WK, Clarke MF, Carlson RW, Stockdale FE, Mollick JA, Chen L, Levy R. Kohrt HE, et al. J Clin Invest. 2012 Mar;122(3):1066-75. doi: 10.1172/JCI61226. Epub 2012 Feb 13. J Clin Invest. 2012. Retraction in: J Clin Invest. 2019 Jun 03;129(6):2595. doi: 10.1172/JCI129688 PMID: 22326955 Free PMC article. Retracted.
Targeting CD137 enhances the efficacy of cetuximab.
Kohrt HE, Colevas AD, Houot R, Weiskopf K, Goldstein MJ, Lund P, Mueller A, Sagiv-Barfi I, Marabelle A, Lira R, Troutner E, Richards L, Rajapaska A, Hebb J, Chester C, Waller E, Ostashko A, Weng WK, Chen L, Czerwinski D, Fu YX, Sunwoo J, Levy R. Kohrt HE, et al. J Clin Invest. 2014 Jun;124(6):2668-82. doi: 10.1172/JCI73014. Epub 2014 May 16. J Clin Invest. 2014. Retraction in: J Clin Invest. 2019 Jun 03;129(6):2595. doi: 10.1172/JCI129689 PMID: 24837434 Free PMC article. Retracted.