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Mouse models of thyroid cancer: A 2015 update.
Kirschner LS, Qamri Z, Kari S, Ashtekar A. Kirschner LS, et al. Mol Cell Endocrinol. 2016 Feb 5;421:18-27. doi: 10.1016/j.mce.2015.06.029. Epub 2015 Jun 27. Mol Cell Endocrinol. 2016. PMID: 26123589 Free PMC article. Review.
Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.
Pringle DR, Vasko VV, Yu L, Manchanda PK, Lee AA, Zhang X, Kirschner JM, Parlow AF, Saji M, Jarjoura D, Ringel MD, La Perle KM, Kirschner LS. Pringle DR, et al. J Clin Endocrinol Metab. 2014 May;99(5):E804-12. doi: 10.1210/jc.2013-3101. Epub 2014 Feb 10. J Clin Endocrinol Metab. 2014. PMID: 24512487 Free PMC article.