R01 CA191191/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	4
2018	5
2019	2
2020	2
2021	2
2022	1
2025	0

1

Discovery of IDO1 Inhibitors: From Bench to Bedside.

Prendergast GC, Malachowski WP, DuHadaway JB, Muller AJ. Prendergast GC, et al. Cancer Res. 2017 Dec 15;77(24):6795-6811. doi: 10.1158/0008-5472.CAN-17-2285. Cancer Res. 2017. PMID: 29247038 Free PMC article. Review.

2

Inflammatory Reprogramming with IDO1 Inhibitors: Turning Immunologically Unresponsive 'Cold' Tumors 'Hot'.

Prendergast GC, Mondal A, Dey S, Laury-Kleintop LD, Muller AJ. Prendergast GC, et al. Trends Cancer. 2018 Jan;4(1):38-58. doi: 10.1016/j.trecan.2017.11.005. Epub 2017 Dec 21. Trends Cancer. 2018. PMID: 29413421 Free PMC article. Review.

3

The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism.

Merlo LMF, Peng W, DuHadaway JB, Montgomery JD, Prendergast GC, Muller AJ, Mandik-Nayak L. Merlo LMF, et al. J Immunol. 2022 Feb 1;208(3):571-581. doi: 10.4049/jimmunol.2100705. Epub 2021 Dec 29. J Immunol. 2022. PMID: 34965962 Free PMC article.

4

Editorial: Targeting Indoleamine 2,3-dioxygenases and Tryptophan Dioxygenase for Cancer Immunotherapy.

Brochez L, Kruse V, Schadendorf D, Muller AJ, Prendergast GC. Brochez L, et al. Front Immunol. 2021 Dec 6;12:789473. doi: 10.3389/fimmu.2021.789473. eCollection 2021. Front Immunol. 2021. PMID: 34938297 Free PMC article. No abstract available.

5

Therapeutic antibody targeting of indoleamine-2,3-dioxygenase (IDO2) inhibits autoimmune arthritis.

Merlo LMF, Grabler S, DuHadaway JB, Pigott E, Manley K, Prendergast GC, Laury-Kleintop LD, Mandik-Nayak L. Merlo LMF, et al. Clin Immunol. 2017 Jun;179:8-16. doi: 10.1016/j.clim.2017.01.016. Epub 2017 Feb 20. Clin Immunol. 2017. PMID: 28223071 Free PMC article.

6

Indoleamine 2,3-Dioxygenase and Its Therapeutic Inhibition in Cancer.

Prendergast GC, Malachowski WJ, Mondal A, Scherle P, Muller AJ. Prendergast GC, et al. Int Rev Cell Mol Biol. 2018;336:175-203. doi: 10.1016/bs.ircmb.2017.07.004. Epub 2017 Sep 21. Int Rev Cell Mol Biol. 2018. PMID: 29413890 Free PMC article. Review.

7

Host IDO2 Gene Status Influences Tumor Progression and Radiotherapy Response in KRAS-Driven Sporadic Pancreatic Cancers.

Nevler A, Muller AJ, Sutanto-Ward E, DuHadaway JB, Nagatomo K, Londin E, O'Hayer K, Cozzitorto JA, Lavu H, Yeo TP, Curtis M, Villatoro T, Leiby BE, Mandik-Nayak L, Winter JM, Yeo CJ, Prendergast GC, Brody JR. Nevler A, et al. Clin Cancer Res. 2019 Jan 15;25(2):724-734. doi: 10.1158/1078-0432.CCR-18-0814. Epub 2018 Sep 28. Clin Cancer Res. 2019. PMID: 30266763 Free PMC article.

8

IDO2 Modulates T Cell-Dependent Autoimmune Responses through a B Cell-Intrinsic Mechanism.

Merlo LM, DuHadaway JB, Grabler S, Prendergast GC, Muller AJ, Mandik-Nayak L. Merlo LM, et al. J Immunol. 2016 Jun 1;196(11):4487-97. doi: 10.4049/jimmunol.1600141. Epub 2016 Apr 25. J Immunol. 2016. PMID: 27183624 Free PMC article.

9

Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses.

Merlo LMF, DuHadaway JB, Montgomery JD, Peng WD, Murray PJ, Prendergast GC, Caton AJ, Muller AJ, Mandik-Nayak L. Merlo LMF, et al. Front Immunol. 2020 Aug 18;11:1861. doi: 10.3389/fimmu.2020.01861. eCollection 2020. Front Immunol. 2020. PMID: 32973768 Free PMC article.

10

A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2.

Nevler A, Muller AJ, Cozzitorto JA, Goetz A, Winter JM, Yeo TP, Lavu H, Yeo CJ, Prendergast GC, Brody JR. Nevler A, et al. J Am Coll Surg. 2018 Apr;226(4):596-603. doi: 10.1016/j.jamcollsurg.2017.12.052. Epub 2018 Feb 7. J Am Coll Surg. 2018. PMID: 29426021 Free PMC article.

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