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Page 1
Comparison of cell response to chromatin and DNA damage.
Luzhin A, Rajan P, Safina A, Leonova K, Stablewski A, Wang J, Robinson D, Isaeva N, Kantidze O, Gurova K. Luzhin A, et al. Nucleic Acids Res. 2023 Nov 27;51(21):11836-11855. doi: 10.1093/nar/gkad865. Nucleic Acids Res. 2023. PMID: 37855682 Free PMC article.
The 3D Genome as a Target for Anticancer Therapy.
Kantidze OL, Gurova KV, Studitsky VM, Razin SV. Kantidze OL, et al. Trends Mol Med. 2020 Feb;26(2):141-149. doi: 10.1016/j.molmed.2019.09.011. Epub 2019 Oct 31. Trends Mol Med. 2020. PMID: 31679987 Free PMC article. Review.
Structure and function of the histone chaperone FACT - Resolving FACTual issues.
Gurova K, Chang HW, Valieva ME, Sandlesh P, Studitsky VM. Gurova K, et al. Biochim Biophys Acta Gene Regul Mech. 2018 Jul 25:S1874-9399(18)30159-7. doi: 10.1016/j.bbagrm.2018.07.008. Online ahead of print. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 30055319 Free PMC article. Review.
Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448).
Heppner DE, Wittlinger F, Beyett TS, Shaurova T, Urul DA, Buckley B, Pham CD, Schaeffner IK, Yang B, Ogboo BC, May EW, Schaefer EM, Eck MJ, Laufer SA, Hershberger PA. Heppner DE, et al. ACS Med Chem Lett. 2022 Nov 10;13(12):1856-1863. doi: 10.1021/acsmedchemlett.2c00213. eCollection 2022 Dec 8. ACS Med Chem Lett. 2022. PMID: 36518696 Free PMC article.
Stimulation of an anti-tumor immune response with "chromatin-damaging" therapy.
Chen M, Brackett CM, Burdelya LG, Punnanitinont A, Patnaik SK, Matsuzaki J, Odunsi AO, Gudkov AV, Singh AK, Repasky EA, Gurova KV. Chen M, et al. Cancer Immunol Immunother. 2021 Jul;70(7):2073-2086. doi: 10.1007/s00262-020-02846-8. Epub 2021 Jan 13. Cancer Immunol Immunother. 2021. PMID: 33439292 Free PMC article.
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors.
Wittlinger F, Ogboo BC, Shevchenko E, Damghani T, Pham CD, Schaeffner IK, Oligny BT, Chitnis SP, Beyett TS, Rasch A, Buckley B, Urul DA, Shaurova T, May EW, Schaefer EM, Eck MJ, Hershberger PA, Poso A, Laufer SA, Heppner DE. Wittlinger F, et al. Commun Chem. 2024 Feb 20;7(1):38. doi: 10.1038/s42004-024-01108-3. Commun Chem. 2024. PMID: 38378740 Free PMC article.
The anti-cancer drugs curaxins target spatial genome organization.
Kantidze OL, Luzhin AV, Nizovtseva EV, Safina A, Valieva ME, Golov AK, Velichko AK, Lyubitelev AV, Feofanov AV, Gurova KV, Studitsky VM, Razin SV. Kantidze OL, et al. Nat Commun. 2019 Mar 29;10(1):1441. doi: 10.1038/s41467-019-09500-7. Nat Commun. 2019. PMID: 30926878 Free PMC article.
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