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Clinically relevant humanized mouse models of metastatic prostate cancer to evaluate cancer therapies.
Kostlan RJ, Phoenix JT, Budreika A, Ferrari MG, Khurana N, Cho JE, Juckette K, McCollum BL, Moskal R, Mannan R, Qiao Y, Griend DJV, Chinnaiyan AM, Kregel S. Kostlan RJ, et al. bioRxiv [Preprint]. 2023 Oct 17:2023.10.13.562280. doi: 10.1101/2023.10.13.562280. bioRxiv. 2023. Update in: Mol Cancer Res. 2024 Sep 4;22(9):826-839. doi: 10.1158/1541-7786.MCR-23-0904 PMID: 37904960 Free PMC article. Updated. Preprint.
Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.
Sundaresan S, Meininger CA, Kang AJ, Photenhauer AL, Hayes MM, Sahoo N, Grembecka J, Cierpicki T, Ding L, Giordano TJ, Else T, Madrigal DJ, Low MJ, Campbell F, Baker AM, Xu H, Wright NA, Merchant JL. Sundaresan S, et al. Gastroenterology. 2017 Dec;153(6):1555-1567.e15. doi: 10.1053/j.gastro.2017.08.038. Epub 2017 Aug 30. Gastroenterology. 2017. PMID: 28859856 Free PMC article.
Menin regulates the serine biosynthetic pathway in Ewing sarcoma.
Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER. Svoboda LK, et al. J Pathol. 2018 Jul;245(3):324-336. doi: 10.1002/path.5085. Epub 2018 May 28. J Pathol. 2018. PMID: 29672864 Free PMC article.
EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma.
Jiménez JA, Apfelbaum AA, Hawkins AG, Svoboda LK, Kumar A, Ruiz RO, Garcia AX, Haarer E, Nwosu ZC, Bradin J, Purohit T, Chen D, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER. Jiménez JA, et al. Mol Cancer Res. 2021 Jul;19(7):1182-1195. doi: 10.1158/1541-7786.MCR-20-0679. Epub 2021 Mar 19. Mol Cancer Res. 2021. PMID: 33741715 Free PMC article.