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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.
Bender MJ, McPherson AC, Phelps CM, Pandey SP, Laughlin CR, Shapira JH, Medina Sanchez L, Rana M, Richie TG, Mims TS, Gocher-Demske AM, Cervantes-Barragan L, Mullett SJ, Gelhaus SL, Bruno TC, Cannon N, McCulloch JA, Vignali DAA, Hinterleitner R, Joglekar AV, Pierre JF, Lee STM, Davar D, Zarour HM, Meisel M. Bender MJ, et al. Cell. 2023 Apr 27;186(9):1846-1862.e26. doi: 10.1016/j.cell.2023.03.011. Epub 2023 Apr 6. Cell. 2023. PMID: 37028428 Free PMC article.
Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis.
Pandey SP, Bender MJ, McPherson AC, Phelps CM, Sanchez LM, Rana M, Hedden L, Sangani KA, Chen L, Shapira JH, Siller M, Goel C, Verdú EF, Jabri B, Chang A, Chandran UR, Mullett SJ, Wendell SG, Singhi AD, Tilstra JS, Pierre JF, Arteel GE, Hinterleitner R, Meisel M. Pandey SP, et al. Cell Host Microbe. 2022 Jul 13;30(7):1003-1019.e10. doi: 10.1016/j.chom.2022.05.006. Epub 2022 Jun 2. Cell Host Microbe. 2022. PMID: 35658976 Free PMC article.
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer.
Thiyagarajan T, Ponnusamy S, Hwang DJ, He Y, Asemota S, Young KL, Johnson DL, Bocharova V, Zhou W, Jain AK, Petricoin EF, Yin Z, Pfeffer LM, Miller DD, Narayanan R. Thiyagarajan T, et al. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2211832120. doi: 10.1073/pnas.2211832120. Epub 2022 Dec 28. Proc Natl Acad Sci U S A. 2023. PMID: 36577061 Free PMC article.
Circulating Microbiota in Cardiometabolic Disease.
Sumida K, Han Z, Chiu CY, Mims TS, Bajwa A, Demmer RT, Datta S, Kovesdy CP, Pierre JF. Sumida K, et al. Front Cell Infect Microbiol. 2022 May 3;12:892232. doi: 10.3389/fcimb.2022.892232. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35592652 Free PMC article. Review.
Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype.
Asemota S, Effah W, Young KL, Holt J, Cripe L, Ponnusamy S, Thiyagarajan T, Hwang DJ, He Y, Mcnamara K, Johnson D, Wang Y, Grimes B, Khosrosereshki Y, Hollingsworth TJ, Fleming MD, Pritchard FE, Hendrix A, Khan F, Fan M, Makowski L, Yin Z, Sasano H, Hayes DN, Pfeffer LM, Miller DD, Narayanan R. Asemota S, et al. Cell Rep. 2023 Dec 26;42(12):113461. doi: 10.1016/j.celrep.2023.113461. Epub 2023 Nov 17. Cell Rep. 2023. PMID: 37979170 Free PMC article.
Fecal microbial transplants as investigative tools in cancer.
Bohm MS, Ramesh AV, Pierre JF, Cook KL, Murphy EA, Makowski L. Bohm MS, et al. Am J Physiol Gastrointest Liver Physiol. 2024 Nov 1;327(5):G711-G726. doi: 10.1152/ajpgi.00171.2024. Epub 2024 Sep 20. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 39301964 Review.
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