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Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
Targeting cancer cell dormancy.
Agudo J, Aguirre-Ghiso JA, Bhatia M, Chodosh LA, Correia AL, Klein CA. Agudo J, et al. Nat Rev Cancer. 2024 Feb;24(2):97-104. doi: 10.1038/s41568-023-00642-x. Epub 2023 Dec 7. Nat Rev Cancer. 2024. PMID: 38062251 Free PMC article.
Dormancy in Breast Cancer.
Dalla E, Sreekumar A, Aguirre-Ghiso JA, Chodosh LA. Dalla E, et al. Cold Spring Harb Perspect Med. 2023 Nov 1;13(11):a041331. doi: 10.1101/cshperspect.a041331. Cold Spring Harb Perspect Med. 2023. PMID: 37037598 Free PMC article. Review.
Packing a Punch against PD-L1.
Capparelli C, Aplin AE. Capparelli C, et al. Cancer Discov. 2022 Jun 2;12(6):1413-1415. doi: 10.1158/2159-8290.CD-22-0301. Cancer Discov. 2022. PMID: 35652219
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress.
Chua V, Lopez-Anton M, Mizue Terai, Ryota Tanaka, Baqai U, Purwin TJ, Haj JI, Waltrich FJ Jr, Trachtenberg I, Luo K, Tudi R, Jeon A, Han A, Chervoneva I, Davies MA, Aguirre-Ghiso JA, Sato T, Aplin AE. Chua V, et al. Sci Signal. 2024 Jun 11;17(840):eadn8376. doi: 10.1126/scisignal.adn8376. Epub 2024 Jun 11. Sci Signal. 2024. PMID: 38861613 Free PMC article.
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth.
Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE. Han A, et al. Cancers (Basel). 2023 Jun 30;15(13):3451. doi: 10.3390/cancers15133451. Cancers (Basel). 2023. PMID: 37444561 Free PMC article.
17 results