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Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation.
Zhang Y, Zhao Z, Huang LA, Liu Y, Yao J, Sun C, Li Y, Zhang Z, Ye Y, Yuan F, Nguyen TK, Garlapati NR, Wu A, Egranov SD, Caudle AS, Sahin AA, Lim B, Beretta L, Calin GA, Yu D, Hung MC, Curran MA, Rezvani K, Gan B, Tan Z, Han L, Lin C, Yang L. Zhang Y, et al. Cell Metab. 2023 Aug 8;35(8):1457-1473.e13. doi: 10.1016/j.cmet.2023.05.009. Epub 2023 Jun 16. Cell Metab. 2023. PMID: 37329887 Free PMC article.
Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance.
Gjuka D, Adib E, Garrison K, Chen J, Zhang Y, Li W, Boutz D, Lamb C, Tanno Y, Nassar A, El Zarif T, Kale N, Rakaee M, Mouhieddine TH, Alaiwi SA, Gusev A, Rogers T, Gao J, Georgiou G, Kwiatkowski DJ, Stone E. Gjuka D, et al. Cancer Cell. 2023 Oct 9;41(10):1774-1787.e9. doi: 10.1016/j.ccell.2023.09.005. Epub 2023 Sep 28. Cancer Cell. 2023. PMID: 37774699 Free PMC article.