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2022 2
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Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon.
Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han L, Campbell I, Mahe MM, McCauley HA, Zhang X, Sundaram N, Hudson JR, Zarsozo-Lacoste A, Pradhan S, Tominaga K, Sanchez JG, Weiss AA, Chatuvedi P, Spence JR, Hachimi M, North T, Daley GQ, Mayhew CN, Hu YC, Takebe T, Helmrath MA, Wells JM. Múnera JO, et al. Cell Stem Cell. 2023 Nov 2;30(11):1434-1451.e9. doi: 10.1016/j.stem.2023.10.002. Cell Stem Cell. 2023. PMID: 37922878 Free PMC article.
p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression.
Efe G, Dunbar KJ, Sugiura K, Cunningham K, Carcamo S, Karaiskos S, Tang Q, Cruz-Acuña R, Resnick-Silverman L, Peura J, Lu C, Hasson D, Klein-Szanto AJ, Taylor AM, Manfredi JJ, Prives C, Rustgi AK. Efe G, et al. Cancer Discov. 2023 Dec 12;13(12):2632-2651. doi: 10.1158/2159-8290.CD-23-0601. Cancer Discov. 2023. PMID: 37676642 Free PMC article.
Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment.
Li N, Zhu Q, Tian Y, Ahn KJ, Wang X, Cramer Z, Jou J, Folkert IW, Yu P, Adams-Tzivelekidis S, Sehgal P, Mahmoud NN, Aarons CB, Roses RE, Thomas-Tikhonenko A, Furth EE, Stanger BZ, Rustgi A, Haldar M, Katona BW, Tan K, Lengner CJ. Li N, et al. Nat Commun. 2023 Nov 30;14(1):7915. doi: 10.1038/s41467-023-43746-6. Nat Commun. 2023. PMID: 38036590 Free PMC article.
In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice.
Bouffi C, Wikenheiser-Brokamp KA, Chaturvedi P, Sundaram N, Goddard GR, Wunderlich M, Brown NE, Staab JF, Latanich R, Zachos NC, Holloway EM, Mahe MM, Poling HM, Vales S, Fisher GW, Spence JR, Mulloy JC, Zorn AM, Wells JM, Helmrath MA. Bouffi C, et al. Nat Biotechnol. 2023 Jun;41(6):824-831. doi: 10.1038/s41587-022-01558-x. Epub 2023 Jan 26. Nat Biotechnol. 2023. PMID: 36702898 Free PMC article.
Human pluripotent stem cell-derived organoids repair damaged bowel in vivo.
Poling HM, Sundaram N, Fisher GW, Singh A, Shiley JR, Nattamai K, Govindarajah V, Cortez AR, Krutko MO, Ménoret S, Anegon I, Kasendra M, Wells JM, Mayhew CN, Takebe T, Mahe MM, Helmrath MA. Poling HM, et al. Cell Stem Cell. 2024 Oct 3;31(10):1513-1523.e7. doi: 10.1016/j.stem.2024.08.009. Epub 2024 Sep 12. Cell Stem Cell. 2024. PMID: 39270642
RFX6 regulates human intestinal patterning and function upstream of PDX1.
Sanchez JG, Rankin S, Paul E, McCauley HA, Kechele DO, Enriquez JR, Jones NH, Greeley SAW, Letourneau-Frieberg L, Zorn AM, Krishnamurthy M, Wells JM. Sanchez JG, et al. Development. 2024 May 1;151(9):dev202529. doi: 10.1242/dev.202529. Epub 2024 May 9. Development. 2024. PMID: 38587174
Regulation of metastatic organotropism.
Dunbar KJ, Efe G, Cunningham K, Esquea E, Navaridas R, Rustgi AK. Dunbar KJ, et al. Trends Cancer. 2024 Dec 27:S2405-8033(24)00279-6. doi: 10.1016/j.trecan.2024.11.012. Online ahead of print. Trends Cancer. 2024. PMID: 39732596 Review.
Using Human Induced Pluripotent Stem Cell-Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations.
Krishnamurthy M, Kechele DO, Broda T, Zhang X, Enriquez JR, McCauley HA, Sanchez JG, McCracken K, Palermo J, Bernieh A, Collins MH, Thomas IH, Neef HC, Heider A, Dauber A, Wells JM. Krishnamurthy M, et al. Gastroenterology. 2022 Oct;163(4):1053-1063.e7. doi: 10.1053/j.gastro.2022.06.083. Epub 2022 Jul 6. Gastroenterology. 2022. PMID: 35803312 Free PMC article.
11 results