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FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma.
Nat Commun. 2024 May 7;15(1):3805. doi: 10.1038/s41467-024-47514-y.
Nat Commun. 2024.
PMID: 38714664
Free PMC article.
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations.
Balasooriya ER, Wu Q, Ellis H, Zhen Y, Norden BL, Corcoran RB, Mohan A, Martin E, Franovic A, Tyhonas J, Lardy M, Grandinetti KB, Pelham R, Soroceanu L, Silveira VS, Bardeesy N.
Balasooriya ER, et al.
Clin Cancer Res. 2024 May 15;30(10):2181-2192. doi: 10.1158/1078-0432.CCR-23-3588.
Clin Cancer Res. 2024.
PMID: 38437671
Free PMC article.
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Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma.
Chaturantabut S, Oliver S, Frederick DT, Kim J, Robinson FP, Sinopoli A, Song TY, Rodriguez DJ, Chang L, Kesar D, He Y, Ching M, Dzvurumi R, Atari A, Tseng YY, Bardeesy N, Sellers WR.
Chaturantabut S, et al.
bioRxiv [Preprint]. 2024 Sep 18:2024.09.16.613045. doi: 10.1101/2024.09.16.613045.
bioRxiv. 2024.
PMID: 39345400
Free PMC article.
Preprint.
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