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2018 6
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Page 1
Protease-activated receptors in health and disease.
Peach CJ, Edgington-Mitchell LE, Bunnett NW, Schmidt BL. Peach CJ, et al. Physiol Rev. 2023 Jan 1;103(1):717-785. doi: 10.1152/physrev.00044.2021. Epub 2022 Jul 28. Physiol Rev. 2023. PMID: 35901239 Free PMC article. Review.
Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression.
Israelyan N, Del Colle A, Li Z, Park Y, Xing A, Jacobsen JPR, Luna RA, Jensen DD, Madra M, Saurman V, Rahim R, Latorre R, Law K, Carson W, Bunnett NW, Caron MG, Margolis KG. Israelyan N, et al. Gastroenterology. 2019 Aug;157(2):507-521.e4. doi: 10.1053/j.gastro.2019.04.022. Epub 2019 May 7. Gastroenterology. 2019. PMID: 31071306 Free PMC article.
Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice.
De Logu F, Nassini R, Hegron A, Landini L, Jensen DD, Latorre R, Ding J, Marini M, Souza Monteiro de Araujo D, Ramírez-Garcia P, Whittaker M, Retamal J, Titiz M, Innocenti A, Davis TP, Veldhuis N, Schmidt BL, Bunnett NW, Geppetti P. De Logu F, et al. Nat Commun. 2022 Feb 3;13(1):646. doi: 10.1038/s41467-022-28204-z. Nat Commun. 2022. PMID: 35115501 Free PMC article.
Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors.
Thomsen ARB, Jensen DD, Hicks GA, Bunnett NW. Thomsen ARB, et al. Trends Pharmacol Sci. 2018 Oct;39(10):879-891. doi: 10.1016/j.tips.2018.08.003. Epub 2018 Sep 1. Trends Pharmacol Sci. 2018. PMID: 30180973 Free PMC article. Review.
Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Hegron A, Peach CJ, Tonello R, Seemann P, Teng S, Latorre R, Huebner H, Weikert D, Rientjes J, Veldhuis NA, Poole DP, Jensen DD, Thomsen ARB, Schmidt BL, Imlach WL, Gmeiner P, Bunnett NW. Hegron A, et al. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2220979120. doi: 10.1073/pnas.2220979120. Epub 2023 May 22. Proc Natl Acad Sci U S A. 2023. PMID: 37216510 Free PMC article.
Calcitonin Related Polypeptide Alpha Mediates Oral Cancer Pain.
Tu NH, Inoue K, Lewis PK, Khan A, Hwang JH, Chokshi V, Dabovic BB, Selvaraj S, Bhattacharya A, Dubeykovskaya Z, Pinkerton NM, Bunnett NW, Loomis CA, Albertson DG, Schmidt BL. Tu NH, et al. Cells. 2023 Jun 21;12(13):1675. doi: 10.3390/cells12131675. Cells. 2023. PMID: 37443709 Free PMC article.
Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain.
Latorre R, Hegron A, Peach CJ, Teng S, Tonello R, Retamal JS, Klein-Cloud R, Bok D, Jensen DD, Gottesman-Katz L, Rientjes J, Veldhuis NA, Poole DP, Schmidt BL, Pothoulakis CH, Rankin C, Xie Y, Koon HW, Bunnett NW. Latorre R, et al. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2112059119. doi: 10.1073/pnas.2112059119. Proc Natl Acad Sci U S A. 2022. PMID: 35110404 Free PMC article.
46 results