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Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Arunagiri A, et al. Protein Sci. 2024 Apr;33(4):e4949. doi: 10.1002/pro.4949. Protein Sci. 2024. PMID: 38511500 Free PMC article.
TOLLIP inhibits lipid accumulation and the integrated stress response in alveolar macrophages to control Mycobacterium tuberculosis infection.
Venkatasubramanian S, Plumlee CR, Dill-McFarland KA, Cohen SB, Gern BH, Rane DA, Meyer MK, Saha A, Hinderstein SA, Pearson GL, Lietzke AC, Pacheco A, Chow YH, Hung CF, Soleimanpour SA, Altman M, Urdahl KB, Shah JA. Venkatasubramanian S, et al. Nat Microbiol. 2024 Apr;9(4):949-963. doi: 10.1038/s41564-024-01641-w. Epub 2024 Mar 25. Nat Microbiol. 2024. PMID: 38528148 Free PMC article.
Untangling the genetics of beta cell dysfunction and death in type 1 diabetes.
Robertson CC, Elgamal RM, Henry-Kanarek BA, Arvan P, Chen S, Dhawan S, Eizirik DL, Kaddis JS, Vahedi G, Parker SCJ, Gaulton KJ, Soleimanpour SA. Robertson CC, et al. Mol Metab. 2024 Aug;86:101973. doi: 10.1016/j.molmet.2024.101973. Epub 2024 Jun 22. Mol Metab. 2024. PMID: 38914291 Free PMC article. Review.
A versatile pumpless multi-channel fluidics system for maintenance and real-time functional assessment of tissue and cells.
Kamat V, Grumbine MK, Bao K, Mokate K, Khalil G, Cook D, Clearwater B, Hirst R, Harman J, Boeck M, Fu Z, Smith LEH, Goswami M, Wubben TJ, Walker EM, Zhu J, Soleimanpour SA, Scarlett JM, Robbings BM, Hass D, Hurley JB, Sweet IR. Kamat V, et al. Cell Rep Methods. 2023 Nov 20;3(11):100642. doi: 10.1016/j.crmeth.2023.100642. Epub 2023 Nov 13. Cell Rep Methods. 2023. PMID: 37963464 Free PMC article.
Associations of Combined Genetic and Lifestyle Risks with Incident Type 2 Diabetes in the UK Biobank.
Zhao C, Hatzikotoulas K, Balasubramanian R, Bertone-Johnson E, Cai N, Huang L, Huerta-Chagoya A, Janiczek M, Ma C, Mandla R, Paluch A, Rayner NW, Southam L, Sturgeon SR, Suzuki K, Taylor HJ, VanKim N, Yin X, Lee CH, Collins F, Spracklen CN. Zhao C, et al. medRxiv [Preprint]. 2024 Dec 16:2024.12.16.24319115. doi: 10.1101/2024.12.16.24319115. medRxiv. 2024. PMID: 39763538 Free PMC article. Preprint.