R01 ES010546/ES/NIEHS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	2
2008	3
2009	4
2010	4
2011	3
2012	6
2013	5
2014	2
2015	6
2016	12
2017	2
2019	3
2020	2
2021	4
2022	1
2023	1
2025	0

1

Mechanisms of drug toxicity and relevance to pharmaceutical development.

Guengerich FP. Guengerich FP. Drug Metab Pharmacokinet. 2011;26(1):3-14. doi: 10.2133/dmpk.dmpk-10-rv-062. Epub 2010 Oct 22. Drug Metab Pharmacokinet. 2011. PMID: 20978361 Free PMC article. Review.

2

Contributions of human enzymes in carcinogen metabolism.

Rendic S, Guengerich FP. Rendic S, et al. Chem Res Toxicol. 2012 Jul 16;25(7):1316-83. doi: 10.1021/tx300132k. Epub 2012 May 10. Chem Res Toxicol. 2012. PMID: 22531028 Free PMC article. Review.

3

Metals in Biology 2016: Molecular Basis of Selection of Metals by Enzymes.

Guengerich FP. Guengerich FP. J Biol Chem. 2016 Sep 30;291(40):20838-20839. doi: 10.1074/jbc.R116.749259. Epub 2016 Jul 26. J Biol Chem. 2016. PMID: 27462079 Free PMC article. Review.

4

Nucleophilic Thiol Proteins Bind Covalently to Abasic Sites in DNA.

Ghodke PP, Matse JH, Dawson S, Guengerich FP. Ghodke PP, et al. Chem Res Toxicol. 2022 Oct 17;35(10):1805-1808. doi: 10.1021/acs.chemrestox.2c00068. Epub 2022 Apr 28. Chem Res Toxicol. 2022. PMID: 35482010

5

Pre-Steady-State Kinetic Analysis of Single-Nucleotide Incorporation by DNA Polymerases.

Su Y, Peter Guengerich F. Su Y, et al. Curr Protoc Nucleic Acid Chem. 2016 Jun 1;65:7.23.1-7.23.10. doi: 10.1002/cpnc.2. Curr Protoc Nucleic Acid Chem. 2016. PMID: 27248785 Free PMC article.

6

Enzymatic bypass of an N⁶-deoxyadenosine DNA-ethylene dibromide-peptide cross-link by translesion DNA polymerases.

Ghodke PP, Gonzalez-Vasquez G, Wang H, Johnson KM, Sedgeman CA, Guengerich FP. Ghodke PP, et al. J Biol Chem. 2021 Jan-Jun;296:100444. doi: 10.1016/j.jbc.2021.100444. Epub 2021 Feb 20. J Biol Chem. 2021. PMID: 33617883 Free PMC article.

7

Protective Role of Glutathione against Peroxynitrite-Mediated DNA Damage During Acute Inflammation.

Ahmed N, Chakrabarty A, Guengerich FP, Chowdhury G. Ahmed N, et al. Chem Res Toxicol. 2020 Oct 19;33(10):2668-2674. doi: 10.1021/acs.chemrestox.0c00299. Epub 2020 Sep 18. Chem Res Toxicol. 2020. PMID: 32894672 Free PMC article.

8

Synthesis and Characterization of Site-Specific O⁶ -Alkylguanine DNA-Alkyl Transferase-Oligonucleotide Crosslinks.

Ghodke PP, Albertolle ME, Johnson KM, Guengerich FP. Ghodke PP, et al. Curr Protoc Nucleic Acid Chem. 2019 Mar;76(1):e74. doi: 10.1002/cpnc.74. Epub 2019 Jan 18. Curr Protoc Nucleic Acid Chem. 2019. PMID: 30657645 Free PMC article.

9

Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals.

Rendic S, Guengerich FP. Rendic S, et al. Chem Res Toxicol. 2015 Jan 20;28(1):38-42. doi: 10.1021/tx500444e. Epub 2014 Dec 19. Chem Res Toxicol. 2015. PMID: 25485457 Free PMC article. Review.

10

Replication of N2,3-ethenoguanine by DNA polymerases.

Zhao L, Christov PP, Kozekov ID, Pence MG, Pallan PS, Rizzo CJ, Egli M, Guengerich FP. Zhao L, et al. Angew Chem Int Ed Engl. 2012 May 29;51(22):5466-9. doi: 10.1002/anie.201109004. Epub 2012 Apr 4. Angew Chem Int Ed Engl. 2012. PMID: 22488769 Free PMC article. No abstract available.

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