R01 ES030546/ES/NIEHS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2019	1
2020	1
2021	6
2022	1
2023	5
2024	1

1

N ⁶-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription.

Liu J, Dou X, Chen C, Chen C, Liu C, Xu MM, Zhao S, Shen B, Gao Y, Han D, He C. Liu J, et al. Science. 2020 Jan 31;367(6477):580-586. doi: 10.1126/science.aay6018. Epub 2020 Jan 16. Science. 2020. PMID: 31949099 Free PMC article.

2

FTO mediates LINE1 m⁶A demethylation and chromatin regulation in mESCs and mouse development.

Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C. Wei J, et al. Science. 2022 May 27;376(6596):968-973. doi: 10.1126/science.abe9582. Epub 2022 May 5. Science. 2022. PMID: 35511947 Free PMC article.

3

m⁶ A RNA methylation: from mechanisms to therapeutic potential.

He PC, He C. He PC, et al. EMBO J. 2021 Feb 1;40(3):e105977. doi: 10.15252/embj.2020105977. Epub 2021 Jan 20. EMBO J. 2021. PMID: 33470439 Free PMC article. Review.

4

METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity.

Dou X, Huang L, Xiao Y, Liu C, Li Y, Zhang X, Yu L, Zhao R, Yang L, Chen C, Yu X, Gao B, Qi M, Gao Y, Shen B, Sun S, He C, Liu J. Dou X, et al. Protein Cell. 2023 Sep 14;14(9):683-697. doi: 10.1093/procel/pwad009. Protein Cell. 2023. PMID: 37030005 Free PMC article.

5

m⁶A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.

Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY. Yang S, et al. Nat Commun. 2019 Jun 25;10(1):2782. doi: 10.1038/s41467-019-10669-0. Nat Commun. 2019. PMID: 31239444 Free PMC article.

6

Globally reduced N⁶-methyladenosine (m⁶A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration.

Li Y, Dou X, Liu J, Xiao Y, Zhang Z, Hayes L, Wu R, Fu X, Ye Y, Yang B, Ostrow LW, He C, Sun S. Li Y, et al. Nat Neurosci. 2023 Aug;26(8):1328-1338. doi: 10.1038/s41593-023-01374-9. Epub 2023 Jun 26. Nat Neurosci. 2023. PMID: 37365312 Free PMC article.

7

ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.

Zhang LS, Xiong QP, Peña Perez S, Liu C, Wei J, Le C, Zhang L, Harada BT, Dai Q, Feng X, Hao Z, Wang Y, Dong X, Hu L, Wang ED, Pan T, Klungland A, Liu RJ, He C. Zhang LS, et al. Nat Cell Biol. 2021 Jul;23(7):684-691. doi: 10.1038/s41556-021-00709-7. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253897 Free PMC article.

8

A lncRNA from the FTO locus acts as a suppressor of the m⁶A writer complex and p53 tumor suppression signaling.

Zhang J, Wei J, Sun R, Sheng H, Yin K, Pan Y, Jimenez R, Chen S, Cui XL, Zou Z, Yue Z, Emch MJ, Hawse JR, Wang L, He HH, Xia S, Han B, He C, Huang H. Zhang J, et al. Mol Cell. 2023 Aug 3;83(15):2692-2708.e7. doi: 10.1016/j.molcel.2023.06.024. Epub 2023 Jul 20. Mol Cell. 2023. PMID: 37478845 Free PMC article.

9

Chromatin and transcriptional regulation by reversible RNA methylation.

Wei J, He C. Wei J, et al. Curr Opin Cell Biol. 2021 Jun;70:109-115. doi: 10.1016/j.ceb.2020.11.005. Epub 2021 Mar 9. Curr Opin Cell Biol. 2021. PMID: 33706173 Free PMC article. Review.

10

Base-resolution quantitative DAMM-seq for mapping RNA methylations in tRNA and mitochondrial polycistronic RNA.

Zhang LS, Ju CW, Jiang B, He C. Zhang LS, et al. Methods Enzymol. 2023;692:39-54. doi: 10.1016/bs.mie.2023.08.001. Epub 2023 Sep 6. Methods Enzymol. 2023. PMID: 37925186 Free PMC article.

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