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Page 1
Functional characterization of Alzheimer's disease genetic variants in microglia.
Yang X, Wen J, Yang H, Jones IR, Zhu X, Liu W, Li B, Clelland CD, Luo W, Wong MY, Ren X, Cui X, Song M, Liu H, Chen C, Eng N, Ravichandran M, Sun Y, Lee D, Van Buren E, Jiang MZ, Chan CSY, Ye CJ, Perera RM, Gan L, Li Y, Shen Y. Yang X, et al. Nat Genet. 2023 Oct;55(10):1735-1744. doi: 10.1038/s41588-023-01506-8. Epub 2023 Sep 21. Nat Genet. 2023. PMID: 37735198 Free PMC article.
Gene regulation in the 3D genome.
Li Y, Hu M, Shen Y. Li Y, et al. Hum Mol Genet. 2018 Aug 1;27(R2):R228-R233. doi: 10.1093/hmg/ddy164. Hum Mol Genet. 2018. PMID: 29767704 Free PMC article. Review.
Genetically encoded chemical crosslinking of RNA in vivo.
Sun W, Wang N, Liu H, Yu B, Jin L, Ren X, Shen Y, Wang L. Sun W, et al. Nat Chem. 2023 Jan;15(1):21-32. doi: 10.1038/s41557-022-01038-4. Epub 2022 Oct 6. Nat Chem. 2023. PMID: 36202986 Free PMC article.
Cell-type-specific 3D epigenomes in the developing human cortex.
Song M, Pebworth MP, Yang X, Abnousi A, Fan C, Wen J, Rosen JD, Choudhary MNK, Cui X, Jones IR, Bergenholtz S, Eze UC, Juric I, Li B, Maliskova L, Lee J, Liu W, Pollen AA, Li Y, Wang T, Hu M, Kriegstein AR, Shen Y. Song M, et al. Nature. 2020 Nov;587(7835):644-649. doi: 10.1038/s41586-020-2825-4. Epub 2020 Oct 14. Nature. 2020. PMID: 33057195 Free PMC article.
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes.
Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M, Tam TW, Jamieson K, Lu SY, Ming GL, Li Y, Yao J, Weiss LA, Dixon JR, Judge LM, Conklin BR, Song H, Gan L, Shen Y. Song M, et al. Nat Genet. 2019 Aug;51(8):1252-1262. doi: 10.1038/s41588-019-0472-1. Epub 2019 Jul 31. Nat Genet. 2019. PMID: 31367015 Free PMC article.
High throughput PRIME editing screens identify functional DNA variants in the human genome.
Ren X, Yang H, Nierenberg JL, Sun Y, Chen J, Beaman C, Pham T, Nobuhara M, Takagi MA, Narayan V, Li Y, Ziv E, Shen Y. Ren X, et al. bioRxiv [Preprint]. 2023 Jul 12:2023.07.12.548736. doi: 10.1101/2023.07.12.548736. bioRxiv. 2023. Update in: Mol Cell. 2023 Dec 21;83(24):4633-4645.e9. doi: 10.1016/j.molcel.2023.11.021 PMID: 37502948 Free PMC article. Updated. Preprint.
11 results