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Cholinergic control of inflammation.
Rosas-Ballina M, Tracey KJ. Rosas-Ballina M, et al. J Intern Med. 2009 Jun;265(6):663-79. doi: 10.1111/j.1365-2796.2009.02098.x. J Intern Med. 2009. PMID: 19493060 Free PMC article. Review.
The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE.
Rosas-Ballina M, Goldstein RS, Gallowitsch-Puerta M, Yang L, Valdés-Ferrer SI, Patel NB, Chavan S, Al-Abed Y, Yang H, Tracey KJ. Rosas-Ballina M, et al. Mol Med. 2009 Jul-Aug;15(7-8):195-202. doi: 10.2119/molmed.2009.00039. Epub 2009 Apr 27. Mol Med. 2009. PMID: 19593403 Free PMC article.
Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats.
Loram LC, Harrison JA, Chao L, Taylor FR, Reddy A, Travis CL, Giffard R, Al-Abed Y, Tracey K, Maier SF, Watkins LR. Loram LC, et al. Brain Behav Immun. 2010 Aug;24(6):959-67. doi: 10.1016/j.bbi.2010.03.008. Epub 2010 Mar 28. Brain Behav Immun. 2010. PMID: 20353818 Free PMC article.