R01 GM124002/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	1
2018	2
2019	5
2021	1
2022	2
2024	2
2025	0

1

Occurrence, function, and biosynthesis of mycofactocin.

Ayikpoe R, Govindarajan V, Latham JA. Ayikpoe R, et al. Appl Microbiol Biotechnol. 2019 Apr;103(7):2903-2912. doi: 10.1007/s00253-019-09684-4. Epub 2019 Feb 18. Appl Microbiol Biotechnol. 2019. PMID: 30778644 Free PMC article. Review.

2

At the confluence of ribosomally synthesized peptide modification and radical S-adenosylmethionine (SAM) enzymology.

Latham JA, Barr I, Klinman JP. Latham JA, et al. J Biol Chem. 2017 Oct 6;292(40):16397-16405. doi: 10.1074/jbc.R117.797399. Epub 2017 Aug 22. J Biol Chem. 2017. PMID: 28830931 Free PMC article. Review.

3

Interrogating the Functions of PRDM9 Domains in Meiosis.

Thibault-Sennett S, Yu Q, Smagulova F, Cloutier J, Brick K, Camerini-Otero RD, Petukhova GV. Thibault-Sennett S, et al. Genetics. 2018 Jun;209(2):475-487. doi: 10.1534/genetics.118.300565. Epub 2018 Apr 19. Genetics. 2018. PMID: 29674518 Free PMC article.

4

Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases.

Lien Y, Lachowicz JC, Mendauletova A, Zizola C, Ngendahimana T, Kostenko A, Eaton SS, Latham JA, Grove TL. Lien Y, et al. ACS Chem Biol. 2024 Feb 16;19(2):370-379. doi: 10.1021/acschembio.3c00583. Epub 2024 Jan 31. ACS Chem Biol. 2024. PMID: 38295270

5

Identification of a poly-cyclopropylglycine-containing peptide via bioinformatic mapping of radical S-adenosylmethionine enzymes.

Kostenko A, Lien Y, Mendauletova A, Ngendahimana T, Novitskiy IM, Eaton SS, Latham JA. Kostenko A, et al. J Biol Chem. 2022 May;298(5):101881. doi: 10.1016/j.jbc.2022.101881. Epub 2022 Mar 31. J Biol Chem. 2022. PMID: 35367210 Free PMC article.

6

Correction to "A structural, biochemical, and bioinformatic basis for identifying radical SAM cyclopropyl synthases.".

Lien Y, Lachowicz JC, Mendauletova A, Zizola C, Ngendahimana T, Kostenko A, Eaton SS, Latham JA, Grove TL. Lien Y, et al. ACS Chem Biol. 2024 May 17;19(5):1206. doi: 10.1021/acschembio.4c00225. Epub 2024 Apr 29. ACS Chem Biol. 2024. PMID: 38683739 Free article. No abstract available.

7

Spectroscopic and Electrochemical Characterization of the Mycofactocin Biosynthetic Protein, MftC, Provides Insight into Its Redox Flipping Mechanism.

Ayikpoe R, Ngendahimana T, Langton M, Bonitatibus S, Walker LM, Eaton SS, Eaton GR, Pandelia ME, Elliott SJ, Latham JA. Ayikpoe R, et al. Biochemistry. 2019 Feb 19;58(7):940-950. doi: 10.1021/acs.biochem.8b01082. Epub 2019 Jan 25. Biochemistry. 2019. PMID: 30628436 Free PMC article.

8

Biosynthesis of the redox cofactor mycofactocin is controlled by the transcriptional regulator MftR and induced by long-chain acyl-CoA species.

Mendauletova A, Latham JA. Mendauletova A, et al. J Biol Chem. 2022 Jan;298(1):101474. doi: 10.1016/j.jbc.2021.101474. Epub 2021 Dec 9. J Biol Chem. 2022. PMID: 34896395 Free PMC article.

9

Mycofactocin Biosynthesis Proceeds through 3-Amino-5-[( p-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone (AHDP); Direct Observation of MftE Specificity toward MftA.

Ayikpoe R, Salazar J, Majestic B, Latham JA. Ayikpoe R, et al. Biochemistry. 2018 Sep 18;57(37):5379-5383. doi: 10.1021/acs.biochem.8b00816. Epub 2018 Sep 6. Biochemistry. 2018. PMID: 30183269 Free PMC article.

10

A two-component protease in Methylorubrum extorquens with high activity toward the peptide precursor of the redox cofactor pyrroloquinoline quinone.

Martins AM, Latham JA, Martel PJ, Barr I, Iavarone AT, Klinman JP. Martins AM, et al. J Biol Chem. 2019 Oct 11;294(41):15025-15036. doi: 10.1074/jbc.RA119.009684. Epub 2019 Aug 19. J Biol Chem. 2019. PMID: 31427437 Free PMC article.

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