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A Polyketide Cyclase That Forms Medium-Ring Lactones.
Gao DW, Jamieson CS, Wang G, Yan Y, Zhou J, Houk KN, Tang Y. Gao DW, et al. J Am Chem Soc. 2021 Jan 13;143(1):80-84. doi: 10.1021/jacs.0c11226. Epub 2020 Dec 22. J Am Chem Soc. 2021. PMID: 33351624 Free PMC article.
Selective Enzymatic Oxidation of Silanes to Silanols.
Bähr S, Brinkmann-Chen S, Garcia-Borràs M, Roberts JM, Katsoulis DE, Houk KN, Arnold FH. Bähr S, et al. Angew Chem Int Ed Engl. 2020 Sep 1;59(36):15507-15511. doi: 10.1002/anie.202002861. Epub 2020 Apr 21. Angew Chem Int Ed Engl. 2020. PMID: 32212229 Free PMC article.
A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases.
Hoffarth ER, Caddell Haatveit K, Kuatsjah E, MacNeil GA, Saroya S, Walsby CJ, Eltis LD, Houk KN, Garcia-Borràs M, Ryan KS. Hoffarth ER, et al. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2012591118. doi: 10.1073/pnas.2012591118. Proc Natl Acad Sci U S A. 2021. PMID: 34580201 Free PMC article.
An Enzymatic Platform for Primary Amination of 1-Aryl-2-alkyl Alkynes.
Liu Z, Qin ZY, Zhu L, Athavale SV, Sengupta A, Jia ZJ, Garcia-Borràs M, Houk KN, Arnold FH. Liu Z, et al. J Am Chem Soc. 2022 Jan 12;144(1):80-85. doi: 10.1021/jacs.1c11340. Epub 2021 Dec 23. J Am Chem Soc. 2022. PMID: 34941252 Free PMC article.
25 results