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Finding the missing heritability of complex diseases.
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TF, McCarroll SA, Visscher PM. Manolio TA, et al. Nature. 2009 Oct 8;461(7265):747-53. doi: 10.1038/nature08494. Nature. 2009. PMID: 19812666 Free PMC article. Review.
Darwinian and demographic forces affecting human protein coding genes.
Nielsen R, Hubisz MJ, Hellmann I, Torgerson D, Andrés AM, Albrechtsen A, Gutenkunst R, Adams MD, Cargill M, Boyko A, Indap A, Bustamante CD, Clark AG. Nielsen R, et al. Genome Res. 2009 May;19(5):838-49. doi: 10.1101/gr.088336.108. Epub 2009 Mar 11. Genome Res. 2009. PMID: 19279335 Free PMC article.
Targets of balancing selection in the human genome.
Andrés AM, Hubisz MJ, Indap A, Torgerson DG, Degenhardt JD, Boyko AR, Gutenkunst RN, White TJ, Green ED, Bustamante CD, Clark AG, Nielsen R. Andrés AM, et al. Mol Biol Evol. 2009 Dec;26(12):2755-64. doi: 10.1093/molbev/msp190. Epub 2009 Aug 27. Mol Biol Evol. 2009. PMID: 19713326 Free PMC article.