R01 HL074136/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2008	1
2009	1
2010	6
2011	1
2015	1
2016	1
2024	0

1

ABC transporters, atherosclerosis and inflammation.

Fitzgerald ML, Mujawar Z, Tamehiro N. Fitzgerald ML, et al. Atherosclerosis. 2010 Aug;211(2):361-70. doi: 10.1016/j.atherosclerosis.2010.01.011. Epub 2010 Jan 21. Atherosclerosis. 2010. PMID: 20138281 Free PMC article. Review.

2

Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.

Tamehiro N, Mujawar Z, Zhou S, Zhuang DZ, Hornemann T, von Eckardstein A, Fitzgerald ML. Tamehiro N, et al. J Biol Chem. 2009 Sep 11;284(37):24881-90. doi: 10.1074/jbc.M109.014365. Epub 2009 Jul 10. J Biol Chem. 2009. PMID: 19592499 Free PMC article.

3

ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.

Sakae N, Liu CC, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, Tachibana M, Younkin L, Kurti A, Carrasquillo MM, Zou F, Sevlever D, Bisceglio G, Gan M, Fol R, Knight P, Wang M, Han X, Fryer JD, Fitzgerald ML, Ohyagi Y, Younkin SG, Bu G, Kanekiyo T. Sakae N, et al. J Neurosci. 2016 Mar 30;36(13):3848-59. doi: 10.1523/JNEUROSCI.3757-15.2016. J Neurosci. 2016. PMID: 27030769 Free PMC article.

4

Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7.

Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S. Tanaka N, et al. J Lipid Res. 2010 Sep;51(9):2591-9. doi: 10.1194/jlr.M006049. Epub 2010 May 22. J Lipid Res. 2010. PMID: 20495215 Free PMC article.

5

HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.

Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S. Tanaka N, et al. Atherosclerosis. 2011 Aug;217(2):407-14. doi: 10.1016/j.atherosclerosis.2011.06.031. Epub 2011 Jun 23. Atherosclerosis. 2011. PMID: 21762915 Free PMC article.

6

LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.

Tamehiro N, Park MH, Hawxhurst V, Nagpal K, Adams ME, Zannis VI, Golenbock DT, Fitzgerald ML. Tamehiro N, et al. Biochemistry. 2015 Nov 24;54(46):6931-41. doi: 10.1021/acs.biochem.5b00894. Epub 2015 Nov 9. Biochemistry. 2015. PMID: 26506427 Free PMC article.

7

Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.

Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M, Fitzgerald ML. Mujawar Z, et al. Biochemistry. 2010 Sep 28;49(38):8338-49. doi: 10.1021/bi100466q. Biochemistry. 2010. PMID: 20731376 Free PMC article.

8

Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux.

Asztalos BF, Mujawar Z, Morrow MP, Grant A, Pushkarsky T, Wanke C, Shannon R, Geyer M, Kirchhoff F, Sviridov D, Fitzgerald ML, Bukrinsky M, Mansfield KG. Asztalos BF, et al. J Infect Dis. 2010 Aug 15;202(4):614-23. doi: 10.1086/654817. J Infect Dis. 2010. PMID: 20617930 Free PMC article.

9

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.

Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML. Tamehiro N, et al. Biochemistry. 2008 Jun 10;47(23):6138-47. doi: 10.1021/bi800182t. Epub 2008 May 17. Biochemistry. 2008. PMID: 18484747 Free PMC article.

10

Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.

Okuhira K, Fitzgerald ML, Tamehiro N, Ohoka N, Suzuki K, Sawada J, Naito M, Nishimaki-Mogami T. Okuhira K, et al. J Biol Chem. 2010 May 21;285(21):16369-77. doi: 10.1074/jbc.M109.061424. Epub 2010 Mar 26. J Biol Chem. 2010. PMID: 20348106 Free PMC article.

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