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Page 1
Shear stress and atherosclerosis.
Heo KS, Fujiwara K, Abe J. Heo KS, et al. Mol Cells. 2014 Jun;37(6):435-40. doi: 10.14348/molcells.2014.0078. Epub 2014 Apr 30. Mol Cells. 2014. PMID: 24781409 Free PMC article. Review.
A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis.
Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. Le NT, et al. Circulation. 2013 Jan 29;127(4):486-99. doi: 10.1161/CIRCULATIONAHA.112.116988. Epub 2012 Dec 14. Circulation. 2013. PMID: 23243209 Free PMC article.
Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents.
Le NT, Takei Y, Izawa-Ishizawa Y, Heo KS, Lee H, Smrcka AV, Miller BL, Ko KA, Ture S, Morrell C, Fujiwara K, Akaike M, Abe J. Le NT, et al. J Immunol. 2014 Oct 1;193(7):3803-15. doi: 10.4049/jimmunol.1400571. Epub 2014 Sep 3. J Immunol. 2014. PMID: 25187658 Free PMC article.
p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.
Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe J. Le NT, et al. Circ Res. 2012 Feb 17;110(4):536-50. doi: 10.1161/CIRCRESAHA.111.254730. Epub 2012 Jan 19. Circ Res. 2012. PMID: 22267842 Free PMC article.
18 results