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Page 1
Acetylation of C/EBPα inhibits its granulopoietic function.
Bararia D, Kwok HS, Welner RS, Numata A, Sárosi MB, Yang H, Wee S, Tschuri S, Ray D, Weigert O, Levantini E, Ebralidze AK, Gunaratne J, Tenen DG. Bararia D, et al. Nat Commun. 2016 Mar 23;7:10968. doi: 10.1038/ncomms10968. Nat Commun. 2016. PMID: 27005833 Free PMC article.
The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.
Staber PB, Zhang P, Ye M, Welner RS, Levantini E, Di Ruscio A, Ebralidze AK, Bach C, Zhang H, Zhang J, Vanura K, Delwel R, Yang H, Huang G, Tenen DG. Staber PB, et al. Blood. 2014 Oct 9;124(15):2391-9. doi: 10.1182/blood-2014-01-550855. Epub 2014 Sep 3. Blood. 2014. PMID: 25185713 Free PMC article.
DNMT1-interacting RNAs block gene-specific DNA methylation.
Di Ruscio A, Ebralidze AK, Benoukraf T, Amabile G, Goff LA, Terragni J, Figueroa ME, De Figueiredo Pontes LL, Alberich-Jorda M, Zhang P, Wu M, D'Alò F, Melnick A, Leone G, Ebralidze KK, Pradhan S, Rinn JL, Tenen DG. Di Ruscio A, et al. Nature. 2013 Nov 21;503(7476):371-6. doi: 10.1038/nature12598. Epub 2013 Oct 9. Nature. 2013. PMID: 24107992 Free PMC article.
PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway.
Zhou J, Wu J, Li B, Liu D, Yu J, Yan X, Zheng S, Wang J, Zhang L, Zhang L, He F, Li Q, Chen A, Zhang Y, Zhao X, Guan Y, Zhao X, Yan J, Ni J, Nobrega MA, Löwenberg B, Delwel R, Valk PJ, Kumar A, Xie L, Tenen DG, Huang G, Wang QF. Zhou J, et al. Leukemia. 2014 Jul;28(7):1436-48. doi: 10.1038/leu.2013.384. Epub 2013 Dec 26. Leukemia. 2014. PMID: 24445817 Free PMC article.
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.
Chen L, Li Y, Lin CH, Chan TH, Chow RK, Song Y, Liu M, Yuan YF, Fu L, Kong KL, Qi L, Li Y, Zhang N, Tong AH, Kwong DL, Man K, Lo CM, Lok S, Tenen DG, Guan XY. Chen L, et al. Nat Med. 2013 Feb;19(2):209-16. doi: 10.1038/nm.3043. Epub 2013 Jan 6. Nat Med. 2013. PMID: 23291631 Free PMC article.
Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.
Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF, Lee S, Ravikumar S, Srivastava S, Tian X, Poon RT, Fan ST, Luk JM, Dan YY, Salto-Tellez M, Chai L, Tenen DG. Yong KJ, et al. N Engl J Med. 2013 Jun 13;368(24):2266-76. doi: 10.1056/NEJMoa1300297. N Engl J Med. 2013. PMID: 23758232 Free PMC article.
27 results